All the Active Ingredient Drugs
Janus Kinase Inhibitor (JAKs). Baricitinib 2 mg, 4 mg. F.C. TABS.: 28. 4 mg ×1/d. A dose of 2 mg×1/d. is approp. for pts. such as those aged ≥ 75 yrs. and may be approp. for pts. with a history of chron. or recur. infect. A dose of 2 mg×1/d may also be consid. for pts. who have achieved sustain. control of dis. active. with 4 mg×1/d and are eligible for dose tapering. Tmt. should not be initiat. in pts. with an absolute lymphocyte count (ALC) less than 0.5 x 109 cells/L, an absolute neutrophil count (ANC) less than 1 x 109 cells/L, or who have a haemoglobin value less than 8 g/dL. Tmt. may be initiat. once values have improv. above these limits. See lit.
Tmt. of moder.- severe active RA in adult pts. who have responded inadequate. to, or who are intolerant to one or more dis.-modif. anti-rheum. drugs. May be used as monother. or in comb. with methotrexate.
C/I: Hypersens. Preg.