All the Drug Class Drugs
Antiplatelet Agent. Tirofiban HCl Monohydrate 0.05 mg/ml. VIAL FOR INJECT: 1 x 12.5 mg/50 ml
INFUS. BAG: 1 x 12.5 mg/250 ml (0.05
mg/ml). Initial: 0.4 μg/kg/min of
diluted sol. by I.V. Then 0.1 μg/kg/min.
In comb. with heparin in unstable
ang. or non-Q-wave M.I., prevent card.
ischem. events, acute coronary syndr.
(incl. medically managed and
undergoing PTCA or atherectomy). See
Antiplatelet Agent. Ticagrelor 60 mg, 90 mg. F.C. TABS: 56, 168. With/out food. Initial.
load. dose: 180 mg (2 tabs) dly cont.
with ASA 75-150 mg dly. Maint: 90 mg
2 x dly. Avoid lapses/discont. ther. due
to poss. risk CV/MI. See lit.
Co-admin. with ASA for prevent.
atherothrombot. events in pts. with Acute
Coronary Syndromes (unstable ang., non
ST elevat. MI (NSTEMI) or ST elevat. MI
(STEMI), pts. managed with PCI/CABG).
C/I: Hypersens., active path. bleed.,
history intracran. hemorrh., med-severe
hepat. impair., co-admin. with strong
CYP3A4 inhibs. See lit.
Antiplatelet Agent. Acetylsalicylic Acid 100 mg. E.C. TABS: 28/30. 75/100 mg dly aft.
diagn. MI: Initial: 150 mg dly. Short
term up to 300 mg dly as reqd. See lit.
Prim. prevent. coron. heart dis. in pts. at
incr. risk, second. prevent. thrombot.
C/I: Known hypersens. to drug/drugs of
same group., bleed. disords., active/
history of recurr. peptic ulcer/
haemorrhage, child/adolesc. under 20
yrs suffering/recover. from influenza/
chicken pox (for fear of Reye’s syndr.),
cerebral hemorrh., sev. heart fail.,
history of bleed./perfor. of the stomach/
intestine related to salic. acid/other
Antiplatelet Agent. Clopidogrel (as hydrogen sulphate) 75 mg. TABS: 30. 75 mg dly as single dose
with/out food. Non-ST seg. elevat.
acute coronary syndr. (unstable
angina/non-Q-wave MI). Initial: 300
mg load. dose, cont. with 75 mg 1 x dly
(with ASA 75-325 mg dly - optimal:
100 mg dly). Max benefit within 3
mths. but can cont. for up to 12 mths.
ST seg. elevat. acute MI: 75 mg 1 x dly.
Load dose (in comb. with ASA with/
without thrombolyts.): Pts. over 75 yrs:
Comb. ther. as soon as possible aft.
onset sympts. Cont. for at least 4 wks.
Under 18 yrs: Safety/efficacy not
Prevent. atherothromb: In pts. with M.I.
(from a few days until less than 35 days),
ischem. stroke (from 7 days-6 mths) or
estab. periph. art. dis. History recent M.I.,
recent stroke, estab. periph. art. dis, to
reduce rate of comb. endpoint new
ischem. stroke (fatal or not), new M.I. (fatal
or not), and other vasc. death. Acute
coron. syndr. [non-ST seg. elevat. acute
coron. syndr. (unstable angina/non-Qwave
M.I.) or ST seg. elevat. acute M.I. ] in
comb. with ASA in medically treat. pts.
eligible for thrombolyt. ther., percutan.
coron. intervent. (with/out stent) or CABG,
to decr. rate comb. endpoint CV death,
M.I., stroke or refract. ischem.