Clopidogrel

4 Drugs classified under this active ingredient

Antiplatelet Agent. Clopidogrel (as hydrogen sulphate) 75 mg.
TABS: 30. 75 mg dly as single dose
with/out food. Non-ST seg. elevat.
acute coronary syndr. (unstable
angina/non-Q-wave MI). Initial: 300
mg load. dose, cont. with 75 mg 1 x dly
(with ASA 75-325 mg dly - optimal:
100 mg dly). Max benefit within 3
mths. but can cont. for up to 12 mths.
ST seg. elevat. acute MI: 75 mg 1 x dly.
Load dose (in comb. with ASA with/
without thrombolyts.): Pts. over 75 yrs:
Comb. ther. as soon as possible aft.
onset sympts. Cont. for at least 4 wks.
Under 18 yrs: Safety/efficacy not
established.
Prevent. atherothromb: In pts. with M.I.
(from a few days until less than 35 days),
ischem. stroke (from 7 days-6 mths) or
estab. periph. art. dis. History recent M.I.,
recent stroke, estab. periph. art. dis, to
reduce rate of comb. endpoint new
ischem. stroke (fatal or not), new M.I. (fatal
or not), and other vasc. death. Acute
coron. syndr. [non-ST seg. elevat. acute
coron. syndr. (unstable angina/non-Qwave
M.I.) or ST seg. elevat. acute M.I. ] in
comb. with ASA in medically treat. pts.
eligible for thrombolyt. ther., percutan.
coron. intervent. (with/out stent) or CABG,
to decr. rate comb. endpoint CV death,
M.I., stroke or refract. ischem.

Antiplatelet Agent. Clopidogrel (as Besylate) 75 mg.
TABS: 30
75 mg dly as single dose with/without food. Non-ST seg. elevat. acute coronary syndr. (unstab. ang. non-Q-wave MI). Init.: 300 mg load. dose, cont. with 75 mg 1 x dly (with ASA 75-325 mg dly – optimal: 100 mg dly). Max benefit within 3 mths. but can cont. for up to 12 mths. ST seg. elevat. acute MI: 75 mg 1 x dly. Load dose (in comb. with ASA with/without thrombolyts.): Pts. over 75 yrs: Init. without load dose. Comb ther. as soon as possible aft. onset sympts. Cont. for at least 4 wks. Atrial fibrillat.: 75 mg 1 x dly with ASA (75-100 mg dly) Under 18 yrs: not indicated.  
Second. prevent. atherothromb: In adult. with M.I.(from a few days until less than 35 d.),.ischem. stroke (from 7 days-6 mths) or estab. periph. art. dis.
Adults with Acute coron. syndr. non-ST seg. elevat. acute coron. syndr. (unstable angina/non-Q-wave M.I.) includ. pts. undergoing stent placement foll. percutan. coron. intervent., in comb. with ASA. ST seg. elevat. acute MI, in comb. with ASA in medically treat. pts. eligible for thrombolyt. ther.
Prevent. atherothromb/thromboemb. events in atrial fibrillat: Adult. with atrial fibrillat. with at least one risk factor for vasc. events, and not suitable for tmt. with VKA, anti-thrombin or anti factor Xa, who have low bleed. risk. in combinat. with ASA for prevent. atherothrombotic/thromboemb. events, includ. stroke.
C/I: Hypersens., severe hep. impair., active path. bleed. as peptic ulc., intracran. hemorrhage. See lit.

Antiplatelet Agent. Clopidogrel (as bisulfate) 75 mg.
TABS: 30 x 75 mg. Adults, elderly: 75
mg 1 x dly, with/out food. Non-ST
segment elevat., acute coron. syndr.
(unstable ang./non-Q-wave MI): Load.
dose: Single 300 mg, foll. by 75 mg 1 x
dly with ASA 75 mg-325 mg dly. ASA
not more than 100 mg. Use up to 12
mths. Max. benefit at 3 mths. ST
segment elevat., acute MI: Single dly
dose: 75 mg initiated with load. dose
in comb. with ASA, with/out
thrombolytics. 75 years and over:
Initiate without load. dose. Comb. ther.
as early as possible aft. sympts. start
and cont. for at least 4 wks. Safety/
efficacy below 18 yrs not established.
No experience in child.
Prevent. atherothromb: In pts. with M.I.
(from a few days until less than 35 days),
ischem. stroke (from 7 days-6 mths) or
estab. periph. art. dis. History recent M.I.,
recent stroke, estab. periph. art. dis, to
reduce rate of comb. endpoint new
ischem. stroke (fatal or not), new M.I.
(fatal or not), and other vasc. death.
Acute coron. syndr. [non-ST seg. elevat.
acute coron. syndr. (unstable angina/
non-Q-wave M.I.) or ST seg. elevat. acute
M.I. ] in comb. with ASA in medically
treat. pts. eligible for thrombolyt. ther.,
percutan. coron. intervent. (with/out
stent) or CABG, to decr. rate comb.
endpoint CV death, M.I., stroke or refract.
ischem.
C/I: Hypersens., severe liver impair.,
active path. bleed. (pept. ulc./intracran.
hemorrh.), lact.

Antiplatelet Agent. Clopidogrel (as hydrogen sulphate) 75 mg, 300 mg.
F.C. TABS: 30 x 75 mg; 4, 30, 100 x 300
mg. 75 mg dly as single dose with/out
food. Non-ST seg. elevat. acute
coronary syndr. (unstable angina/non-
Q-wave MI). Initial: 300 mg load. dose,
cont. with 75 mg 1 x dly (with ASA
75-325 mg dly - optimal: 100 mg dly).
Max benefit within 3 mths. but can
cont. for up to 12 mths. ST seg. elevat.
acute MI: 75 mg 1 x dly. Load dose (in
comb. with ASA with/without
thrombolyts.): Pts. over 75 yrs: Comb.
ther. as soon as possible aft. onset
sympts. Cont. for at least 4 wks. Under
18 yrs: Safety/ efficacy not established.
Prevent. atherothromb.: In adults with M.I.
(from a few days until less than 35 days),
ischem. stroke (from 7 days-6 mths) or
estab. periph. art. dis. Adults with acute
coron. syndr. non-ST seg. elevat. acute
coron. syndr. (unstable angina/non-Qwave
M.I.), includ. pts. undergoing stent
placement foll. percutan. coron. intervent.,
in comb. with ASA in medically treat. pts.
eligible for thrombolyt. ther. Prevent.
atherothromb/thromboemb. events in
atrial fibrillat: Adults with atrial fibrillat.
with at least one risk factor for vasc.
events, and not suitable for tmt. with VKA,
anti-thrombin or anti factor Xa, who have
low bleed. risk. in combinat. with ASA for
prevent.
atherothrombotic/thromboemb. events,
includ. stroke.
C/I: Hypersens., severe hep. impair.,
active path. bleed. as peptic ulc., intracr.
haemorrhage.