All the Therapeutic System Drugs
α2 Agonist. Brimonidine Tartrate 1.5 mg/ml. OPHTH. SOLN: 5 ml. 1 drop in affect.
eye(s) x 3 dly, approx. every 8 hrs.
Reduct. of elevated IOP in pts. with openangle glaucoma or ocular hypertens.
C/I: Hypersens., neonates and infants
under 2 yrs old.
Carbonic Anhydrase Inhibitor, Nonselective β-Blocker. Brinzolamide 10 mg/ml, Timolol Maleate 5 mg/ml. BOTTLE: 5 ml. 1 dr ×2/d in conjunctival sac of the affected eye(s). See lit.
Decrease of intra-ocular pressure (IOP) in adult pts. with open-ang. glauc. or ocular hypertens. for whom monother. provides insuffic. IOP reduct.
C/I: Hypersens. Hypersens. to other β-block. Hypersens. to sulphonamides.
Reactive airway dis. include. bronch. asthma/history of bronch. asthma, or severe COPD. Sinus bradycardia, sick sinus synd., sino-atrial block, 2nd/3rd degree AV block not control. with pace-maker. Overt CF, cardiogenic shock. Severe allergic rhinitis. Hyperchloraemic acidosis. Sev. renal impair.
Carbonic Anhydrase Inhibitor. Brinzolamide 1%. OPHTH. DROPS (Suspension): 5 ml. 1
drop into affect. eye(s) 2 - 3 x dly.
Elevat. IOP in oc. hypertens., open angle
glaucoma.
C/I: Hypersens. to compos.,
sulphonamides.
Prostaglandin, β Blocker. Bimatoprost 0.3 mg/ml, Timolol Maleate 5 mg/ml. BOTTLE: 3 ml. 1 dr.×1/d, in the morn. or in the eve., in each eye that requires tmt.
Reduction of intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to topical beta-blockers or prostaglandin analogues.
C/I: Hypersens. to bimatoprost, timolol, beta block. Pts. with respirat. disord. such as asthma or severe COPD. Patients with cardiac disorders such as bradycardia, heart block or heart failure. Lact.
Bimatoprost 0.3mg/1ml. BOTTLE (eye dr.): 3 ml. The generally accepted dosage is: one drop of Bimatoprost in the evening, once a day, in each eye that requires treatment. Do not use more than once a day as the treatment’s efficiency may be reduced. Reduction of elevated intraocular pressure in chronic open angle glaucoma and ocular hypertension (as monotherapy or as adjunctive therapy to beta-blockers). C/I: Hypersens. History of hypersens.to benzalkonium chloride.
α2 Agonist. Brimonidine Tartrate 0.15% w/v. OPHTH. SOLN: 5 ml. 1 drop 2 x dly.
When IOP peaks in afternoon or
additional IOP control need: 1 drop
may be added in the afternoon. May
be used concom. with other ophth.
prods. to be admin. at least 5 mins
apart. Not recommend. child 2-12 yrs.
Lower. IOP with open-angle glaucoma or
oc. hypertens.
C/I: Known hypersens., pts. receiving
MAOI’s; lactation; child under 2 yrs.
