All the Therapeutic System Drugs
Carbonic Anhydrase Inhibitor, Nonselective β-Blocker. Brinzolamide 10 mg/ml, Timolol Maleate 5 mg/ml. BOTTLE: 5 ml. 1 dr ×2/d in conjunctival sac of the affected eye(s). See lit.
Decrease of intra-ocular pressure (IOP) in adult pts. with open-ang. glauc. or ocular hypertens. for whom monother. provides insuffic. IOP reduct.
C/I: Hypersens. Hypersens. to other β-block. Hypersens. to sulphonamides.
Reactive airway dis. include. bronch. asthma/history of bronch. asthma, or severe COPD. Sinus bradycardia, sick sinus synd., sino-atrial block, 2nd/3rd degree AV block not control. with pace-maker. Overt CF, cardiogenic shock. Severe allergic rhinitis. Hyperchloraemic acidosis. Sev. renal impair.
Prostaglandin, β Blocker. Bimatoprost 0.3 mg/ml, Timolol Maleate 5 mg/ml. BOTTLE: 3 ml. 1 dr.×1/d, in the morn. or in the eve., in each eye that requires tmt.
Reduction of intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to topical beta-blockers or prostaglandin analogues.
C/I: Hypersens. to bimatoprost, timolol, beta block. Pts. with respirat. disord. such as asthma or severe COPD. Patients with cardiac disorders such as bradycardia, heart block or heart failure. Lact.
α2 Agonist. Brimonidine Tartrate 0.15% w/v. OPHTH. SOLN: 5 ml. 1 drop 2 x dly.
When IOP peaks in afternoon or
additional IOP control need: 1 drop
may be added in the afternoon. May
be used concom. with other ophth.
prods. to be admin. at least 5 mins
apart. Not recommend. child 2-12 yrs.
Lower. IOP with open-angle glaucoma or
C/I: Known hypersens., pts. receiving
MAOI’s; lactation; child under 2 yrs.
α2 Agonist, β Blocker. Brimonidine Tartrate 2 mg/ml, Timolol Maleate 5 mg/ml. OPHTH. SOLN: 5 ml. 1 drop in affect.
eye/s 2 x dly (± every 12 hrs.). If using
more than one top. ophth. soln, use 10
Chron. open-angle glaucoma, ocular
hypertens. not suffic. respond. to IOP
reduct. monother. or use not appropriate.
C/I: Hypersens., bronch. asth./history
thereof, severe chron. obstruct. pulm.
dis., sinus bradycard., 2nd/3rd degree
atrioventric block, overt card. fail.,
cardogen shock, MAOI ther.