Drugs Disributed by Merck Serono LTD, Israel
Progestogen. Progesterone 8% w/w. Sgle. use prefill. vag. gel applic.:6,15 X1.125 g. Infert. due to inad. luteal phase: 1 applic/day start. after docum. ovul. or arbitr. on the 18th-21st-day of the cycle. For in- vitro fertil., when infertil. is due to tubal, idiopathic or endometriosis linked steril. assoc. with normal cycles: 1 app/day for 30 days if there is lab evid. of pregn. Infert. due to inadeq. luteal phase. In- vitro fertil., when infertil. is due to tubal, idiopathic,or endometriosis linked steril. assoc. with normal cycles.
C/I:Hypersens, Undiagn. vag. bleeding. Known or susp. progest.-sensit. malign. tumors. Porphyria. Thrombophleb., thromboembolic dis, cereb. apoplexy, or pts. with an history of these condit. Missed abort.
Immunosuppressant. Cladribine 10 mg. Tab: 1/4/6X 10 mg: 3.5 mg/kg bw over 2 years, admin. as 1 tmt. course of 1.75 mg/kg per year. Tmt. course consists of 2 tmt. weeks, one at the beginn. of the first month and one at the beginn. of the sec. month of the respect. tmt. year. See prescr. info.
Tmt. of adlt. pts. with high. act. relaps. multiple sclerosis (MS) as by clinical or imaging features
C/I: Hypersens.
HIV.
Act. chron. infect. (tuberculosis or hepatitis).
Init. of this tmt. in immunocomprom. pts, incl. pts. on
immunosuppr. or myelosuppr. ther. (See prescr. info).
Act. malign.
Mod. or sev. renal impair. (creat. clear. <60 mL/min) (See prescr. info).
Pregn. and breast-feed.
Protein Kinase Inhibitor. Tepotinib (as hydrochloride hydrate) 225 mg. FC tabs:60 Two tabs, once/day
Tmt. of adlt pts. with metastatic non-small cell lung
cancer (NSCLC) harbouring a MET tyrosine kinase receptor exon 14 (METex14) skip. mut.
C/I:Hypersens., see prescr. info. for full details.