• Home
  • A-B index
  • Pharmacological Index
  • Drug Classes
  • Active Ingredients
  • Companies
  • News
  • Cladribine
    2 Drugs classified under this active ingredient


    All the Active Ingredient Drugs

    Litak 10
    Pharmalogic
    RX
    partial basket chart
    Litak 10

    Antimetabolite (purine analog). Cladribine 10 mg / 5 ml.
    VIALS: 1,5. HCL: S.C: 0.14 mg/kg bdy wt/
    day (5.6 mg/m2/day) for 5 consec. days.
    I.V. (Contin. infus.): Single course for 7
    consec. days: 0.09 mg/kg/day (3.6 mg/
    m2/day). CLL: S.C: 0.1 mg/kg bdy wt/
    day for 5 consec. days (4.0 mg/ m2/
    day). I.V: 2 hrs. on days 1-5 of 28 day
    cycle at dose of 0.10 mg/kg/day (4.0
    mg/m2 /day). Determine pt. response
    every 2 cycles of tmt. In respond. pts.
    (lymphocyt. reduct. of 50% or more)
    repeat for 2 cycles. In non-respond.
    pts. discont. aft. 2 cycles.
    Hairy cell leuk. (HCL), chronic lymphocyt.
    leuk.(CLL), second line tmt. low grade
    Non-Hodgkins lymphoma (NHL).

    Mavenclad
    Merck Serono LTD, Israel
    RX
    partial basket chart
    Mavenclad

    Immunosuppressant. Cladribine 10 mg.
    Tab: 1/4/6X 10 mg: 3.5 mg/kg bw over 2 years,  admin. as 1 tmt. course of 1.75 mg/kg per year. Tmt. course consists of 2 tmt. weeks, one at the beginn. of the first month and one at the beginn. of the sec. month of the respect. tmt. year. See prescr. info.
    Tmt. of adlt. pts. with high. act. relaps. multiple sclerosis (MS) as by clinical or imaging features
    C/I: Hypersens.
    HIV.
    Act. chron. infect. (tuberculosis or hepatitis).
    Init. of this tmt. in immunocomprom. pts, incl. pts. on
    immunosuppr. or myelosuppr. ther. (See prescr. info).
    Act. malign.
    Mod. or sev. renal impair. (creat. clear. <60 mL/min) (See prescr. info).
    Pregn. and breast-feed.

    CLOSE