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  • Antimetabolite (purine analog)
    4 Drugs classified under this drug class

    All the Drug Class Drugs

    Fludarabin “Ebewe” 50 mg / 2 ml
    partial basket chart
    Fludarabin “Ebewe” 50 mg / 2 ml

    Antimetabolite (purine analog). Fludarabine Phosphate 50 mg / 2 ml.
    VIAL: 1 x 50 mg/2 ml. I.V use. Dos.
    accord. to indicat., cond., ren. funct.,
    concur. chemother., blood counts. See lit.
    Palliative tmt. CLL refract. to other ther.
    Tmt. less malign. non-Hodgkin lymphom.
    stage 3-4 not respond. to standard ther.
    with at least one alkylat. agent, dis.
    progress during/aft. standard ther. B-cell
    CLL. Initial tmt or aft. first line ther., in pts
    with suffic. bone marrow reserves.
    C/I: Hypersens., impair. ren. funct.
    (creatinine clear. < 30 ml/min), decomp.
    hemolyt. anem., pregn., lact. See lit.

    Fluorouracil 50 mg/ml
    Salomon, Levin & Elstein Ltd
    partial basket chart
    Fluorouracil 50 mg/ml

    Antimetabolite (purine analog). Fluorouracil 50 mg/ml.
    VIALS: 1 x 1,000 mg/20 ml. 1 x 5,000
    mg/100 ml. See lit.
    Palliative in cancer of breast, stomach,
    pancreas , colon and rectum.

    Litak 10
    partial basket chart
    Litak 10

    Antimetabolite (purine analog). Cladribine 10 mg / 5 ml.
    VIALS: 1,5. HCL: S.C: 0.14 mg/kg bdy wt/
    day (5.6 mg/m2/day) for 5 consec. days.
    I.V. (Contin. infus.): Single course for 7
    consec. days: 0.09 mg/kg/day (3.6 mg/
    m2/day). CLL: S.C: 0.1 mg/kg bdy wt/
    day for 5 consec. days (4.0 mg/ m2/
    day). I.V: 2 hrs. on days 1-5 of 28 day
    cycle at dose of 0.10 mg/kg/day (4.0
    mg/m2 /day). Determine pt. response
    every 2 cycles of tmt. In respond. pts.
    (lymphocyt. reduct. of 50% or more)
    repeat for 2 cycles. In non-respond.
    pts. discont. aft. 2 cycles.
    Hairy cell leuk. (HCL), chronic lymphocyt.
    leuk.(CLL), second line tmt. low grade
    Non-Hodgkins lymphoma (NHL).

    full basket chart

    Antimetabolite (purine analog). Mercaptopurine 50 mg.
    TABS: 25. See lit.
    Acute leukem., chron. myelogen. leukem.
    espec. in child.