Bisphosphonate

7 Drugs classified under this drug class

Bisphosphonate. Zoledronic Acid 5 mg / 100 ml.
SOL. FOR INFUS: 1 x 100 ml.
Single I.V. infus. 5 mg x 1 yr. See lit.
Tmt. Paget’s dis. of bone. Tmt. osteoporos.
post-menopaus. women, men at incr. risk
fracture, incl. recent low trauma hip
fracture. Tmt./prevent. glucocorticoidinduc.
osteoporos. Prevent. post
menopaus. osteoporos. in women when
biphosphonate ther. indicat.
C/I: Hypersens. to excips. or any
bisphosphonates, hypocalcem., pregn.,
lact., sev. ren. impair. (CLcr<35 mL/min).

Bisphosphonate. Risedronate Sodium 150 mg.
TABS.:1,2,3,4. Tab wkly. to be swallowed whole and not sucked or chewed in an upright position with glass of plain water, at least 30 mins. bef. first food, other medicine or drink (except water) of the day. Pts should not lie down for 30 mins aft. taking tab.
Tmt. of postmenopaus. osteoporosis. Prevent. of postmenopaus. osteoporosis
C/I:  Hypersens. Hypocalcaem. Preg., lact.
Severe renal impair.(CrCl <30 ml/min).
Inabil. to stand or sit upright for at least 30 min.

Bisphosphonate. Alendronate (as sodium) 70 mg.
TABS: 4. 1 x 70 mg tab 1 x wkly.
Tmt. osteoporos. in postmenopaus.
woman to prevent fractures, incl. hip and
spine.
C/I: Hypersens., esoph. abnorm., inabil.
to stand or sit for at least 30 mins.

Bisphosphonate. Alendronic Acid 70 mg, Cholecalciferol 140 mcg.
TABS: 4. 1 tab 1 x wkly at least 1/2 hr.
bef. first food, beverage or medicat. of
day, with full glass plain water only, to
be swallowed whole, in upright
position. Not to lie down for at least 30
mins. and until after first food.
Tmt. osteoporos. in postmenopaus.
women, to reduce incidence fractures
hip and spine, to incr. bone mass in men
with osteoporos.
C/I: Esophag. abnorms, inability to
stand/sit upright for at least 30 mins.,
hypocalcem., hypersens. See lit.

Bisphosphonate. Alendronate (as sodium) 70 mg.
TABS: 4 x 70 mg. 1 tab 1 x wkly.
Tmt. osteopor. in post-menopaus.
women to prevent fractures, incl. hip,
spine (vertebral compress. fractures).
C/I: Inability to stand or sit upright for at
least 30 mins., hypocalcem., esophagus
abnormal., hypersens. See lit.

Bisphosphonate. Risedronate Sodium 35 mg.
TABS: 4. 1 tab wkly. to be
swallowed whole and not sucked or
chewed in an upright position with
glass of plain water, at least 30 mins.
bef. first food, other medicine or drink
(except water) of the day. Pts should
not lie down for 30 mins aft. taking
tab.
Tmt. postmenopaus. osteoporos:,
established postmenopaus.
osteopor,
prevent. osteopor. in postmenopaus.
women with incr. risk of osteopor. Tmt.
osteopor. in men, at high risk of
fracture.
C/I: Known hypersens., hypocalcem.,
pregn. lact., severe ren. impair.