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  • Synthomycine 3%
    / Abic


    Active Ingredient

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Ointment

    10 gr

    full basket chart 2090 19206

    Dosage

    Patients should be cautioned to report to their physician if no improvement in their condition occurs after 4-5 days of treatment.
    Apply to the infected area 3-4 times daily after cleansing.


    Indications

    Antibiotic.
    Chloramphenicol is effective against certain protozoa, Rickettsia and virus-like
    infections, as well as against many Gram-positive and Gram-negative bacteria. It is useful in the treatment of superficial pyodermas, impetigo, acute folliculitis,
    seborrhea-like streptodermatitis, and infectious eczematoid dermatitis.


    Contra-Indications

    Known hypersensitivity to chloramphenicol or to any other ingredient of the
    preparation.
    Patients with a known personal or family history of blood dyscrasias including
    aplastic anaemia should avoid use of this product.


    Special Precautions

    See prescribing information for full details.


    Side Effects

    See prescribing information for full details.


    Drug interactions

    The concomitant administration of chloramphenicol with other drugs liable to
    depress bone marrow function should be avoided.


    Pregnancy and Lactation

    Systemically absorbed forms of chloramphenicol enter the fetal circulation and are distributed into breast milk. If given systemically to the mother shortly before parturition or whilst breastfeeding, chloramphenicol may cause bone marrow suppression of the neonate or the “grey baby syndrome”, characterized by cyanosis and hypothermia, owing to the limited glucuronidating capacity of the newborn infant’s liver. Therefore, this product is not recommended for use during pregnancy and lactation.


    Overdose

    Accidental ingestion of the drug is unlikely to cause any toxicity due to the low
    content of antibiotic. It is advisable to keep medication out of reach of children. If accidentally ingested by infants or young children, a local Poisons Information Center should be contacted. As there is individual variability in the pharmacokinetics of chloramphenicol in infants and children monitor plasma levels. Levels exceeding 25 micrograms/mL are frequently considered toxic.


    Manufacturer
    Teva Pharmaceutical Industries Ltd, Israel
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