Presentation and Status in Health Basket
Presentation | Basket | Yarpa | Pharmasoft |
---|---|---|---|
Vial 1 x 500 mg |
1656 | 16085 | |
Vial 1 x 1 g |
1657 | 16078 | |
Vial 1 x 2 gr |
35249 | 16866 |
Dosage
Parenteral drug products should be inspected visually for particulate matter and
discoloration, prior to administration, whenever solution and container permit.
The recommended dosages are given below:
In stubborn, severe infections, a higher dosage may be administered.
Adults: 250-500 mg every 6 hours, by intramuscular or intravenous injection.
Gonorrhea: 2 doses of 500 mg spaced 12 hours apart. Treatment may be repeated if necessary.
Children: 12.5 mg/kg bodyweight every 6 hours, by intramuscular or intravenous injection.
Note: Larger doses may be required for stubborn or severe infections. The children’s dosage is intended for individuals whose weight will not cause a dosage to be calculated greater than that recommended for adults.
Septicemia
Adults: A daily dosage of 8-14 g is recommended, starting with IV administration for at least 3 days and continuing with the IM route every 3-4 hours.
Children: A daily dosage of 150-200 mg/kg body weight is recommended, starting with IV administration for at least 3 days and continuing with the IM route every 3-4 hours.
Bacterial Meningitis caused by N. Meningitidis or H. Influenzae
Adults: A few adults have been treated with doses ranging from 8-14 g daily. Treatment was initiated with intravenous drip therapy for at least 3 days, and continued with frequent (every 3-4 hours) IM therapy.
Children: Children have been treated with doses of 150-200 mg/kg body weight/ day. Treatment was initiated with intravenous drip therapy for at least 3 days, and continued with frequent (every 3-4 hours) IM therapy.
Indications
Infections of respiratory tract, urinary tract, skin and soft tissue, gastro-intestine infections due to gram +tive and gram ?ve bacterial infections.
Contra-Indications
Known hypersensitivity to a penicillin-type drug. Should not be administered to babies born to mothers with a history of hypersensitivity to a penicillin-type drug.
See prescribing information for full details.
Special Precautions
Serious anaphylactoid reactions require immediate emergency treatment with adrenaline. Patients suffering from mononucleosis, pregnancy and lactation, use in infants. In the treatment of group A ?hemolytic streptococcal infections, therapy with this drug should be continued for at least 10 days. Following completion of treatment, cultures should be taken. Assessment of renal, hepatic and hematopoietic functions should be made during prolonged therapy. See prescribing information for full details.
Side Effects
Anaphylaxis, erythematous maculopapular rashes, urticaria and occasional cases of exfoliative dermatitis, erythema multiforme and Stevens-Johnson syndrome, laryngeal edema, chills, fever, edema and arthralgia, glossitis, stomatitis, black “hairy” tongue, nausea, vomiting, enterocolitis, pseudomembranous colitis and diarrhea.
See prescribing information for full details.
Drug interactions
N/A