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  • Neo-Medrol Acne Lotion
    / Pfizer


    Active Ingredient *
    Methylprednisolone (acetate) 2.5 mg/ml
    Neomycin Sulphate 2.5 mg/ml
    Sulfur 50 mg/ml

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Lotion

    25 ml

    full basket chart 1453 14071

    Dosage

    After careful cleansing of the affected skin to minimise the possibility of introducing infection, NEO-MEDROL Acne Lotion should be applied sparingly to the affected areas once or twice a day initially. Avoid contact with the eyes. The frequency of application is dependent upon patients’ susceptibility to the drying effect of the lotion, and may have to be reduced to every other day in some patients.


    Indications

    NEO-MEDROL Acne Lotion is used for the treatment of acne.


    Contra-Indications

    In tuberculosis of the skin, herpes simplex, vaccinia, varicella and in other cutaneous infections which do not respond to neomycin.
    Hypersensitivity to the active substance or to any of the excipients.


    Special Precautions

    Avoid contact with eyes. If signs of irritation or sensitivity develop, application should be discontinued. As with any antibiotic containing product, overgrowth by resistant organisms may occur, particularly monilia. If this occurs, discontinue treatment and institute appropriate measures. Articles in current medical literature indicate an increase in the incidence of patients allergic to neomycin. The possibility of such a reaction should be borne in mind.
    If extensive areas are treated or if the occlusion technique is used, the possibility exists of increased absorption of the corticosteroid and suitable precautions should be taken. The prolonged use of antibiotic-containing preparations may result in overgrowth of nonsusceptible organisms, particularly fungi. If new infections appear during treatment, appropriate therapy should be instituted.
    Convulsions have been reported with concurrent use of methylprednisolone and cyclosporine. Since concurrent administration of these agents results in a mutual inhibition of metabolism, it is possible that convulsions and other adverse events associated with the individual use of either drug may be more apt to occur.
    Ototoxicity and nephrotoxicity have been reported following absorption of topically applied neomycin.
    Pregnancy: Although topical steroids have not been reported to have an adverse effect on pregnancy, the safety of their use has not absolutely been established. Therefore, use with care during pregnancy.
    Children: When topical corticosteroids are applied for a prolonged period of time, sufficient systemic absorption can suppress the hypothalamic-pituitary-adrenal axis. Growth suppression may also occur.


    Side Effects

    The following local adverse reactions have been reported with topical corticosteroids, either with or without occlusive dressings: burning sensation, itching, irritation, dryness, folliculitis, secondary infection, skin atrophy, striae, hypertrichosis, acneiform, eruptions, allergic contact dermatitis, laceration of the skin and hypopigmentation.
    See prescribing information for full details.


    Pregnancy and Lactation

    Pregnancy: Although topical steroids have not been reported to have an adverse effect on pregnancy, the safety of their use has not absolutely been established. Therefore, use with care during pregnancy.


    Manufacturer
    Patheon Inc. Canada
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