Hycomycin Ointment

/ Teva

Apply to the affected area 3-4 times daily.

Allergic dermatoses and other corticosteroid-responsive inflammatory skin diseases, including atopic dermatitis, contact dermatitis, seborrheic dermatitis, anogenital pruritus, infantile eczema, and external otitis.

Known hypersensitivity to any ingredient of the preparations.
Topical corticosteroids are contraindicated in fungal infections, tuberculosis of the skin, varicella and herpes simplex. They should not be applied in the external auditory canal of patients with perforated eardrum.

Rebound effect
Long term continuous or inappropriate use of topical steroids can result in the
development of rebound flares after stopping treatment (topical steroid withdrawal syndrome). A severe form of rebound flare can develop which takes the form of a dermatitis with intense redness, stinging and burning that can spread beyond the initial treatment area. It is more likely to occur when delicate skin sites such as the face and flexures are treated. Should there be a reoccurrence of the condition within days to weeks after successful treatment a withdrawal reaction should be suspected.
Visual disturbance

Visual disturbance may be reported with systemic topical corticosteroid use. If a patient presents with symptoms such as blurred vision or other visual disturbances, the patient should be considered for referral to an ophthalmologist for evaluation of possible causes which may include cataract, glaucoma or rare diseases such as central serous chorioretinopathy (CSCR) which have been reported after use if systemic and topical corticosteroids.
Paediatric population
A possibility of increased absorption exists in very young children: in neonates and infants, absorption by immature skin may be enhanced, and renal function may be immature.
In infants and children, long-term continuous topical therapy should be avoided where possible, as adrenal suppression can occur even without occlusion. In infants, the napkin may act as an occlusive dressing, and increase absorption.
General
* Any spread of infection requires withdrawal of topical corticosteroid therapy, and systemic administration of antimicrobial agents.
* As with all corticosteroids prolonged application to the face is undesirable.
* Not intended for ophthalmic use.
* Extended or recurrent application may increase the risk of contact sensitisation.
* Extension of infection may occur due to the masking effect of the steroid.
* Following significant systemic absorption, aminoglycosides such as neomycin can cause irreversible ototoxicity; and neomycin has nephrotoxic potential.
* In renal impairment the plasma clearance of neomycin is reduced.
* Products which contain antimicrobial agents should not be diluted.
Excipient with known effect
This medical center contains lanolin anhydrous, that may cause local skin reactions (e.g. contact dermatitis).
This medicine contains methylparaben (Methyl p-hydroxybenzoate (E218)), that may cause allergic reactions (possibly delayed).

See prescribing information for full details.

Following significant systemic absorption, neomycin can intensify and prolong the respiratory depressant effects of neuromuscular blocking agents. However, the neuromuscular blocking activity of neomycin sulfate is unlikely to present a hazard during use of this preparation.