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  • Epirubicin Inovamed
    / Inovamed


    Active Ingredient
    Epirubicin HCl 2 mg/ml

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Solution for Injection

    50 ml x 2 mg/ml

    partial basket chart

    Related information


    Dosage

    See prescribing information for full details.


    Indications

    For the treatment of a wide spectrum of neoplastic diseases including breast carcinoma, lung carcinoma high doses, ovarian carcinoma, gastric carcinomas, soft tissue sarcoma. Intravesical administration of epirubicin has been found to be beneficial in the treatment of superficial bladder carcinomas and in the prophylaxis of recurrences after transurethral resection. I.V. administration for the treatment of advanced bladder carcinoma.


    Contra-Indications

    By I.V. route: Known hypersensitivity to epirubicin. Severe bone marrow depression following previous chemotherapy and/or radiotherapy. Patients already treated with anthracyclines such as doxorubicin or daunorubicin up to the relevant maximum cumulative dose. Acute infections and existing inflammation of the buccal and/or GI mucosa. Progressive heart failure, arrhythmia and conductive disorders with serious hemodynamic effects, acute inflammatory myocardial conditions, unstable angina pectoris, acute myocardial infarction or myocardial infarction within previous 6 months, cardiomyopathy.By intravesical route: Should not be given by intravesical instillation for the treatment of invasive tumors penetrating the bladder wall.


    Special Precautions

    See prescribing information for full details.


    Side Effects

    Myelosuppression and cardiotoxicity, nausea, vomiting and mucositis, reversible alopecia.
    See prescribing information for full details.


    Drug interactions

    Heparin, anticytostatic agents, alkaline solutions. For list of compatible diluting solutions – see prescribing information for full details.


    Manufacturer
    Genepharm SA
    Licence holder
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