SSRI

18 Drugs classified under this drug class

SSRI. Escitalopram (as Oxalate) 10, 15, 20 mg.
F.C. TABS: 28. Single dly dose with/
without food. Depress: Usual dose: 10
mg 1 x dly. Depend. on individ.
response, dose may be incr. to max. of
20 mg dly. Panic disords: Initial: 5 mg
for 1st wk. bef. incr. dose to 10 mg dly.
Depend on individ. response may incr.
to max. of 20 mg dly. Elderly (> 65 yrs.):
1/2 initial dose and lower max. dose.
See lit.
Depress., panic disords., gen. anxiety
disord. (GAD), social anxiety disord. (SAD).
C/I: Serotonin syndr., child under 18 yrs.,
lact. See lit.

SSRI. Citalopram (as hydrobromide) 20 mg, 40 mg.
TABS: (blister pack): 28 x 20 mg, 40 mg.
Single dly. dose. Initial: 20 mg dly to a max. of 40 mg dly. Over 65 yrs: 1/2 recommend.
dose (10-20 mg dly). Effects usually set in aft. 2-4 wks. Not for child./adolesc. < 18 yrs.
See lit.
Tmt. states of depression, panic disords.
C/I: Combined use of 5-HT agonists with
an SSRI, hypersens. to compon. Pts.
receiv. MAOI’s. See lit.

SSRI. Escitalopram 10 mg, 20 mg.
SCORED TABS: 30 x 10 mg, 20 mg. Panic disord: Initial: 5 mg dly for 1st wk, bef. incr. to 10 mg dly, up to 20 mg dly, depend. on individ. pt. response. Max. effect aft. approx. 3 mths. Tmt. lasts several mths. GAD: 10 mg 1 x dly. Depend. individ. response, may incr. to max 20 mg dly. Tmt. for 3 mths to consolidate response. Longer-term tmt. of responders may be considered to prevent relapse. SAD: 10 mg 1 x dly for 2-4 wks to obtain sympt. relief. Depend. pt. response, decr. to 5 mg or incr. to max. 20 mg dly. Tmt. for 3 mths to prevent releapse. Long-term tmt. of responders for 6 mths to prevent relapse to be consider. on individ. basis. Tmt. benefits to be re-eval. at reg. intervals. OCD: 10 mg 1 x dly. Depend.
on individ. pt. response, may be incr. to 20 mg dly. Long-term. tmt. of pts. respond. to 16 wk. open tmt. phase has been studied for at least 24 wks. in pts. receiv. 10 or 20 mg dly. As OCD is a chron. dis., treat for sufficient period to ensure they are sympt. free. This may be several months or longer. Tmt. depress., see sec. 3 (k).
Tmt. panic disorders, general. anxiety disord. (GAD), social anxiety disord. (SAD, social phobia, obsessive-compulsive disord (OCD).
C/I: Known hypersens., concomit. tmt. with non-select. irreversible MAOI’s, pimozide.

SSRI. Escitalopram (as Oxalate) 10, 15, 20 mg.
F.C. TABS: 28. Single dly dose with/
without food. Depress: Usual dose: 10
mg 1 x dly. Depend. on individ.
response, dose may be incr. to max. of
20 mg dly. Panic disords: Initial: 5 mg
for 1st wk. bef. incr. dose to 10 mg dly.
Depend on individ. response may incr.
to max. of 20 mg dly. Elderly (> 65
yrs.): 1/2 initial dose and lower max. dose.
Depress., panic disords., gen. anxiety
disord. (GAD), social anxiety disord.
(SAD), Obsess. compuls. disords.
C/I: Serotonin syndr., child under 18 yrs.,
lact. See lit.

SSRI. Fluvoxamine Maleate 50 mg, 100 mg.
TABS: 60 x 50 mg, 10, 30 x 100 mg. 100-
200 mg dly. accord. to pt. response, to
max. of 300 mg dly. Minimum start.
dose: 100 mg dly. as single dose in
evening. Total dly. dose of more than
100 mg to be given in 2-3 div. doses.
Tmt. depression, obsess. compuls. disords.
C/I: In comb. MAOI’s. Can be given 2 wks
aft. discont. of irreverse. MAOI or foll. day
aft. discont. reverse. MAOI (e.g.
moclobemide). At least 1 wk. betw.
discont. fluvoxamine and start of any
MAOI. Known hypersens.

SSRI. Fluoxetine HCl 20 mg.
CAPS: 10, 30. Initial: 20 mg/day in the
morn. If no clinical improv. aft. several
wks. can admin. b.i.d. but nor more
than 80 mg/day. See lit. Binge - eat.
and vomit. behav. in bulimia nervosa:
Initial: 60 mg/day in the morn. Use
lower dose in hepat. impair., elderly,
concurent dis, multiple concom.
medicat. See lit.
Depression, OCD.