• Home
  • A-B index
  • Pharmacological Index
  • Drug Classes
  • Active Ingredients
  • Companies
  • News
  • Soluble Guanylate Cyclase Stimulator
    2 Drugs classified under this drug class


    All the Drug Class Drugs

    Adempas
    Bayer
    RX
    partial basket chart
    Adempas

    Soluble Guanylate Cyclase Stimulator. Riociguat 0.5, 1, 1.5, 2, 2.5 mg.
    F.C. TABS.: 42×0.5mg, 1mg, 1.5mg, 42, 84×2mg, 84×2.5mg. The recomm. start. dose is 1 mg×3/d for 2 wks. approx. 6 to 8 hrs. apart. incr. by 0.5 mg×3/d every two wks. to a max. of 2.5 ×3/d, if systole. blood press. is ≥95 mmHg and the pt. has no signs or sympt. of hypotens.
    Maint.dose The max. total dly. dose is 7.5 mg i.e., 2.5 mg ×3/d. If a dose is missed, tmt. should be cont. with the next dose as planned. See lit.
    CTEPH, Pts. with WHO Funct. class II to III: Inoperable CTEPH, Persist./ recur. CTEPH after surg. tmt., to improve exercise capacity. PAH: as monother. /combination with endothelin receptor antag., tmt. of adult pts. with PAH with WHO Funct. class II to III to improve exercise capacity. Effic.has been shown in a PAH population including aetiologies of idiopathic or heritable PAH or PAH assoc. with connect. tissue dis.
    C/I: Hypersens. Co-adm. with PDE 5 inhib. (e.g sildenafil, tadalafil, vardenafil). Sev. hep. impair. (Child Pugh C). Co-adm. with nitrates or nitric oxide donors (e.g. amyl nitrite) in any form. Pts. with systolic
    blood pressure < 95 mm Hg at tmt. init.

    Verquvo
    Bayer
    RX
    not in the basket chart
    Verquvo

    Soluble Guanylate Cyclase Stimulator. Vericiguat 2.5 mg , 5 mg , 10 mg.
    FC Tabs:14/28/98 X 2.5/5/10 mg: . 2.5 mg vericiguat once daily. Dose to be doubl. approx every 2 weeks to reach maint. dose of 10 mg once daily, as toler. See  full prescript. info
    To red. the risk of cardiovascular death and heart failure (HF) hospital. following a hospital. for HF or need for outpatient IV diuretics, in adults with sympt. chron. HF and EF less than 45%.
    C/I:Hypersens, Concom. use of other sol. guanylate cyclase (sGC) stim., such as riociguat

    CLOSE