All the Drug Class Drugs
Quinolone. Ciprofloxacin (as HCl) 3 mg/ml. EYE AND EAR DROPS (SOL.): 5 ml.
Adults and child from 1 yr:
Corneal ulc.: 2 drops every 15 mins. for
first 6 hrs., then 2 drops every 30 mins.
for rest of day. 2nd day: 2 drops hrly.
On 3rd-14th day: 2 drops every 4 hrs.
for up to 14 days.
Bact. conjunct: 1-2 drops into conjuct.
sac(s) every 2 hrs. for 2 days, then 1-2
drops every 4 hrs. for next 5 days.
Otic use: 3 to 4 drops, 2-4 /d, or more
frequently, if required.
In gen., the duration of tmt does not
exceed 5-10 ds.
For either ind. a max. duration of ther.
of 21 days is recommend.
Corneal ulc., conjunct. caused by suscep.
gram pos., gram neg. microorg. for adults
and ped. pts > 1 yr.
For local./diff. otitis externa accomp. by a
strong inflamm. react. and of which the
strains are suscept., and for the acute flare-up of a chronic otitis media. In this
case, a mucopurulent secret.
In other infect. of the ear in which
Pseudom. aerug. and/or other suscept.
strains may be suspect., it can be used
under the strict superv. of an ear specialist.
It must be understood that this is not a
routine tmt and improper use must be
avoided.
C/I: Hypersens. to the product or other
quinolones.
Quinolone. Ciprofloxacin (as hydrochloride) 500 mg. CAPS: 10 × 500mg. Upper & lower respir. tract infect.: 500-
750mg 2 x dly.
UTI: 250-500mg 2 x dly. (in premenopaus.
women, 500 mg single
dose may be used).
Genital tract infect.: Gonococ. urethritis
&cervicitis: 500mg as a single dose.
Epididymo-orchitis and pelvic inflamm.
Dis.: 500-750mg 2 x dly.
Infec. of the GI tract and intra-abdom.
infect., Diarrhoea caused by bacterial
pathogens include. Shigella spp. other
than Shigella dysenteriae type 1 and
empirical tmt. of severe travellers’
diarrhea, Diarrhoea caused by Shigella
dysenteriae type 1, Diarrhoea caused
by Vibrio cholera, Typhoid fever :
500mg x 2 dly.
Intra-abdom. infec. due to Gramnegative
bacteria: 500-750mg 2 x dly.
Infec. of the skin and soft tissue: 500-
750mg 2 x dly.
Bone & joint infec. : 500-750mg 2 x dly.
Neutropenic pts. with fever suspected
to be due to a bact. infec.
Ciprofloxacin should be co-admin. with
appropriate antibact. agent(s) in
accordance to official guidance: 500-
750mg 2 x dly over the entire period of
neutropenia.
Prophylax. of invas. infec. due to
Neisseria meningitides: 500 mg as a
single dose.
Inhal. anthrax post-exposure
prophylax. and curative tmt. for
persons able to receive tmt. by oral
route when clinical. appropriate. Drug
admin. should begin as soon as
possible after suspected or confirmed
exposure: 500mg 2 x dly.
See lit.
Ped. pts.:
CF: 20 mg/kg bdy. wt. twice dly. with a
max.of 750 mg/dose.
Complic. UTI and pyelonephritis: 10
mg/kg bdy. wt. twice dly. to 20 mg/kg
bdy. wt. twice dly. with a max. of 750
mg/ dose.
Inhal. anthrax post-exposure
prophylax. & curative tmt. for persons
able to receive tmt. by oral route when
clinical. appropr. Drug admin. should
begin as soon as possible after suspect.
or confirmed exposure: 10 mg/kg bdy.
wt. twice dly. to 15 mg/kg bdy. wt.
twice dly. with a max.of 500 mg/ dose.
Other severe infec.: 20 mg/kg bdy. wt.
twice dly. with a max. of 750 mg/dose.
See lit.
Elderl.: should receive a dose selected
accord.to the sever.of the infec. and the
pts. CrCl.
Pts. with renal.& hep. impair.: see lit.
Adult.: Broad spectr. antibiotic for infec.
caused by ciprofloxacin sensit.
pathogens.
Child., adolesc.: Broncho-pulmon. infec.
in CF caused by Pseudomonas a.
Complic. UTI, pyelonephritis.
Inhal. anthrax (post-exposure prophylax. & curative tmt.). May also be used to treat
severe infec. in child.& adolesc. when
there is no other alternative .
Tmt. should be initiat.only by physicians
who are experienc. in the tmt. of CF and/
or severe infec. in childr., adolesc.
C/I: Hypersens. to ciprofloxacin or other
quinolones.
Concom. admin. with Tizanidine. See lit.
Quinolone. Ciprofloxacin (HCl) 250, 500, 750 mg. TABS: 10. Upper and lower respir. tract
infects: 250-750 mg 2 x dly. Upper and
lower urin. tract infects: 250-500 mg 2
x dly. Pneumococ. pneumon. and cystic
fibros. pts. with P. infects. of lower
respir. tract: 750 mg 2 x dly. Other
infects: 500-750 mg 2 x dly. For ped.
cystic fibros. pts. aged 5-17 yrs. with
acute pulm. exacerbat. assoc. with P.
aeruginosa infects: 20 mg/kg 2 x dly.
Max. dly dose: 1,500 mg.
Infects. caused by ciprofloxacin-sens.
pathogens: tmt. invas. infect. extern. ear;
tmt. acute pulm. exacerbat. of cystic
fibrosis assoc. with Pseudomonas
aeruginosa in ped. pts. aged 5-17 yrs.
C/I: Known hypersens. to ciprofloxacin or
other quinolone deriv., child. and grow.
adolesc., pregn., lact.
Quinolone. Ciprofloxacin (as lactate) 2 mg/ml. INFUS. BAGS (sol. for infus.): 1, 5, 10, 12 x
100 ml, 200 ml x 2 mg/ml. See lit.
Infects. caused by ciprofloxacin-sens.
pathogens, tmt. acute pulm. exacerbat.
of cystic fibrosis assoc. with
Pseudomonas aeruginosa in ped. pts.
aged 5-17 yrs.
C/I: Known hypersens. to ciprofloxacin
or other quinolone deriv., child. and
grow. adolesc., pregn., lact.
Quinolone. Levofloxacin (as Hemihydrate) 500 mg. TABS: 5. 1 tab 1-2 x dly for up to 14
days.
Mild to mod. infects. incl. acute sinusit.,
acute chron. bronchit., common acq.
pneumon., complicat. urin. tract infects.,
skin and soft tissue infects.
C/I: Hypersens., epilepsy, fluroquinolone
related tendon disords., pregn., lact.,
child up to 18 yrs.
Quinolone. Levofloxacin 5 mg/ml. Sol. (infus.) 10 x 50 ml; 100 ml polyolefin bags. Commun.-acquir.pneum.- 500 mg once, twice dly. Compl. UTI , pyelonephrit. 250 mg×1/d. Skin, soft tissue infec.- 250 mg mg×1/d. Pts. with renal impair. dose ajust. is needed.
Commun. acquir. pneum., Compl. UTI , pyelonephrit., Skin and soft tiss.infec.
C/I: Hypersens., hypersens. to quinolones, fluoroquinolone related tendon disords., epilepsy, pts. under 18 yrs, preg., lact.
