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  • Quinolone
    15 Drugs classified under this drug class


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    Ciloxan
    Novartis
    RX
    partial basket chart
    Ciloxan

    Quinolone. Ciprofloxacin (as HCl) 3 mg/ml.
    EYE AND EAR DROPS (SOL.): 5 ml.
    Adults and child from 1 yr:
    Corneal ulc.: 2 drops every 15 mins. for
    first 6 hrs., then 2 drops every 30 mins.
    for rest of day. 2nd day: 2 drops hrly.
    On 3rd-14th day: 2 drops every 4 hrs.
    for up to 14 days.
    Bact. conjunct: 1-2 drops into conjuct.
    sac(s) every 2 hrs. for 2 days, then 1-2
    drops every 4 hrs. for next 5 days.
    Otic use: 3 to 4 drops, 2-4 /d, or more
    frequently, if required.
    In gen., the duration of tmt does not
    exceed 5-10 ds.
    For either ind. a max. duration of ther.
    of 21 days is recommend.
    Corneal ulc., conjunct. caused by suscep.
    gram pos., gram neg. microorg. for adults
    and ped. pts > 1 yr.
    For local./diff. otitis externa accomp. by a
    strong inflamm. react. and of which the
    strains are suscept., and for the acute flare-up of a chronic otitis media. In this
    case, a mucopurulent secret.
    In other infect. of the ear in which
    Pseudom. aerug. and/or other suscept.
    strains may be suspect., it can be used
    under the strict superv. of an ear specialist.
    It must be understood that this is not a
    routine tmt and improper use must be
    avoided.
    C/I: Hypersens. to the product or other
    quinolones.

    Ciprodex 500
    Dexcel
    RX
    partial basket chart
    Ciprodex 500

    Quinolone. Ciprofloxacin (as hydrochloride) 500 mg.
    CAPS: 10 × 500mg. Upper & lower respir. tract infect.: 500-750mg 2 x dly.
    UTI: 250-500mg 2 x dly. (in premenopaus.
    women, 500 mg single dose may be used).
    Genital tract infect.: Gonococ. urethritis
    & cervicitis: 500mg as a single dose.
    Epididymo-orchitis and pelvic inflamm.
    Dis.: 500-750mg 2 x dly.
    Infec. of the GI tract and intra-abdom.
    infect., Diarrhoea caused by bacterial
    pathogens include. Shigella spp. other
    than Shigella dysenteriae type 1 and
    empirical tmt. of severe travellers’
    diarrhea, Diarrhoea caused by Shigella
    dysenteriae type 1, Diarrhoea caused
    by Vibrio cholera, Typhoid fever: 500mg x 2 dly.
    Intra-abdom. infec. due to Gramnegative
    bacteria: 500-750mg 2 x dly.
    Infec. of the skin and soft tissue: 500-
    750mg 2 x dly.
    Bone & joint infec.: 500-750mg 2 x dly.
    Neutropenic pts. with fever suspected
    to be due to a bact. infec.
    Ciprofloxacin should be co-admin. with
    appropriate antibact. agent(s) in
    accordance to official guidance: 500-
    750mg 2 x dly over the entire period of
    neutropenia.
    Prophylax. of invas. infec. due to
    Neisseria meningitides: 500 mg as a
    single dose.
    Inhal. anthrax post-exposure prophylax. and curative tmt. for persons able to receive tmt. by oral route when clinical. appropriate. Drug admin. should begin as soon as possible after suspected or confirmed exposure: 500mg 2 x dly. See lit.
    Ped. pts.: CF: 20 mg/kg bdy. wt. twice dly. with a max.of 750 mg/dose.
    Complic. UTI and pyelonephritis: 10
    mg/kg bdy. wt. twice dly. to 20 mg/kg
    bdy. wt. twice dly. with a max. of 750
    mg/dose.
    Inhal. anthrax post-exposure prophylax. & curative tmt. for persons able to receive tmt. by oral route when clinical. appropr. Drug admin. should begin as soon as possible after suspect. or confirmed exposure: 10 mg/kg bdy. wt. twice dly. to 15 mg/kg bdy. wt. twice dly. with a max.of 500 mg/ dose.
    Other severe infec.: 20 mg/kg bdy. wt.
    twice dly. with a max. of 750 mg/dose.
    See lit.
    Elderl.: should receive a dose selected
    accord.to the sever.of the infec. and the
    pts. CrCl. Pts. with renal.& hep. impair.: see lit.
    Adult.: Broad spectr. antibiotic for infec.
    caused by ciprofloxacin sensit.
    pathogens.
    Child., adolesc.: Broncho-pulmon. infec.
    in CF caused by Pseudomonas a.
    Complic. UTI, pyelonephritis.
    Inhal. anthrax (post-exposure prophylax. & curative tmt.). May also be used to treat
    severe infec. in child.& adolesc. when
    there is no other alternative.
    Tmt. should be initiat.only by physicians
    who are experienc. in the tmt. of CF and/
    or severe infec. in childr., adolesc.
    C/I: Hypersens. to ciprofloxacin or other
    quinolones.
    Concom. admin. with Tizanidine. See lit.

    Ciprofloxacin Teva
    Teva
    RX
    partial basket chart
    Ciprofloxacin Teva

    Quinolone. Ciprofloxacin (HCl) 250, 500, 750 mg.
    TABS: 10. Upper and lower respir. tract
    infects: 250-750 mg 2 x dly. Upper and
    lower urin. tract infects: 250-500 mg 2
    x dly. Pneumococ. pneumon. and cystic
    fibros. pts. with P. infects. of lower
    respir. tract: 750 mg 2 x dly. Other
    infects: 500-750 mg 2 x dly. For ped.
    cystic fibros. pts. aged 5-17 yrs. with
    acute pulm. exacerbat. assoc. with P.
    aeruginosa infects: 20 mg/kg 2 x dly.
    Max. dly dose: 1,500 mg.
    Infects. caused by ciprofloxacin-sens.
    pathogens: tmt. invas. infect. extern. ear;
    tmt. acute pulm. exacerbat. of cystic
    fibrosis assoc. with Pseudomonas
    aeruginosa in ped. pts. aged 5-17 yrs.
    C/I: Known hypersens. to ciprofloxacin or
    other quinolone deriv., child. and grow.
    adolesc., pregn., lact.

    Ciprofloxacin Teva Infusion Bags
    Abic
    RX
    not in the basket chart
    Ciprofloxacin Teva Infusion Bags

    Quinolone. Ciprofloxacin (as lactate) 2 mg/ml.
    INFUS. BAGS (sol. for infus.): 1, 5, 10, 12 x
    100 ml, 200 ml x 2 mg/ml. See lit.
    Infects. caused by ciprofloxacin-sens.
    pathogens, tmt. acute pulm. exacerbat.
    of cystic fibrosis assoc. with
    Pseudomonas aeruginosa in ped. pts.
    aged 5-17 yrs.
    C/I: Known hypersens. to ciprofloxacin
    or other quinolone deriv., child. and
    grow. adolesc., pregn., lact.

    Levo
    Unipharm
    RX
    not in the basket chart
    Levo

    Quinolone. Levofloxacin (as Hemihydrate) 500 mg.
    TABS: 5. 1 tab 1-2 x dly for up to 14
    days.
    Mild to mod. infects. incl. acute sinusit.,
    acute chron. bronchit., common acq.
    pneumon., complicat. urin. tract infects.,
    skin and soft tissue infects.
    C/I: Hypersens., epilepsy, fluroquinolone
    related tendon disords., pregn., lact.,
    child up to 18 yrs.

    Levofloxacin Teva
    Abic
    RX
    not in the basket chart
    Levofloxacin Teva

    Quinolone. Levofloxacin 5 mg/ml.
    Sol. (infus.) 10 x 50 ml; 100 ml polyolefin bags. Commun.-acquir.pneum.- 500 mg once, twice dly. Compl. UTI , pyelonephrit. 250 mg×1/d. Skin, soft tissue infec.- 250 mg mg×1/d. Pts. with renal impair. dose ajust. is needed.
    Commun. acquir. pneum., Compl. UTI , pyelonephrit., Skin and soft tiss.infec.
    C/I: Hypersens., hypersens. to quinolones, fluoroquinolone related tendon disords., epilepsy, pts. under 18 yrs, preg., lact.

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