All the Drug Class Drugs
Estrogen, Progesterone. Estradiol (as Hemihydrate) 3.2 mg, Norethisterone Acetate 11.2 mg. PATCH (transderm.): 8. Applied individ.
without interruption. TDSs should be
applied twice wkly., every three- four
days, to the trunk below the waist.
Hormone replac. therapy (HRT) for the
relief of menopausal sympt.
C/I: Hypersens. Known current/ past or
suspect. breast canc. Known/ suspect.
estrogen-depend. malig. tumors (e.g.
endomet. cancer) or pre-malign.
tumors (e.g. untreated atyp. endomet.
hyperplas.). Undiagnosed gen. bleed. Preg. / lact. Acute liver dis.,/ history of
liver dis. as long as liver func. tests
have failed to return to normal.
Previous/current ven.
thromboembolism (DVT, pulmon.
embol.). Known thrombophilic
conditions (e.g. protein C, protein S or
antithrombin defic. Active/recent past
arterial thromboembolic dis. (e.g. CVA,
angina, MI). Porphyria.
