Nitrates

5 Drugs classified under this drug class

Nitrates. Isosorbide Mononitrate 20 mg, 40 mg.
TABS: 30, 60 x 20 mg, 30 x 40 mg. 40-60
mg dly. Protect. ang: may incr. to 120
mg dly.
Tmt. ang. pect., prevent. ang. attacks.
Tmt. CHF.
C/I: Hypersens.
Acute MI with low filling press., acute circulat. fail. (shock, vascul. collapse), very low blood press. (systolic blood press. below 90 mmHg), HOCM, constrict. pericardit., card. tamponade, low card. filling press., aortic/mitral valve stenosis, diseases with raised intracran. press. e.g. following head trauma and includ. cereb. haemorrhage.
Pts. with sev. anaemia, sev. hypotens.
Pts. with closed angle glaucoma.
Pts. with sev. hypovolaem.
Concom. with PDE-5 inhib. (e.g. sildenafil, tadalafil, vardenafil).
Concom. use  with riociguat.
See Lit.

Nitrates. Isosorbide Mononitrate 50 mg.
SR Tab: 30. 1 tab in morning. Incr. to 2 tabs. dly. in morning.

Tmt. ang. pect., prevent. ang. attacks.

C/I:

Hypersens.,

Acute MI with low filling press., acute circulat. fail. (shock, vascul. collapse), very low blood press. (systolic blood press. below 90 mmHg), HOCM, constrict. pericardit., card. tamponade, low card. filling press., aortic/mitral valve stenosis, diseases with raised intracran. press. e.g. following head trauma and including cereb. Haemorrhage,
Pts. with sev. anaemia, severe hypotens.
Pts. with closed angle glaucoma.
Pts. with severe hypovolaemia.
Concom. with PDE-5 inhib. (e.g. sildenafil, tadalafil, vardenafil),
Concom. with riociguat. See lit.

Nitrates. Isosorbide Mononitrate 40 mg.
S.R. CAPS: 30. 1 cap. or in severe cases 2 caps. dly.
Prevent. and tmt. of angina pectoris.
C/I: Hypersens. 
Acute MI with low filling pressure, acute circulatory failure, very low BP, hypertrophic obstructive cardiomyop., constrict. Pericard., cardiac tamponade, low cardiac fill. press., aortic/mitral valve stenosis and dis. assoc. with raised intra-cranial press.
Severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia. Concom. use with Phosphodiesterase type-5 inhibitors or riociguat.

  

Nitrates. Nitroglycerine 25 mg, 50 mg.
ADHESIVE PLASTER: 10 (in vivo releases
5 mg, 10 mg nitroglycerine/ 24 hrs.).
Apply 1 plaster in 24 hrs.
Proph. attacks ang. pect.
C/I: Hypersens. Acute circulat. fail. assoc.
with marked hypotens.(shock). Condit.
assoc. with elev. intracran. pres.
Myocard. insuffic. due to obstruct., as in
aortic or mitral stenosis or constrict.
pericarditis. Concom. use with PDE5
inhib. e.g. sildenafil. Severe hypotens.
(systole. blood pres.<90 mmHg). Severe
hypovolemia. The onset of action of
transder. nitroglycerin is not suffic. rapid
for this product to be useful in aborting an acute attack. Allergy to the adhesives
used in nitroglycerin patches.

Nitrates. Glyceryl Trinitrate 0.4 mg/spray jet.
METERED DOSE SPRAY: Single Pack: 1 x
14.2 g (250 puffs). Dual Pack: 2 x 4.9 g (75 puffs) + 14.2 g (250 puffs)/per pack.
0.4 mg-0.8 mg (1-2 sprays) under
tongue when reqd. If no response,
repeat aft. 10 mins.
Relief and proph. ang. pect.