All the Drug Class Drugs
COMT Inhibitor. Entacapone 200 mg. F.C. TABS: 30. 1 tab with ea. levodopa/
dopa-decarboxylase inhib. admin.
Max. dly dose: up to 2,000 mg.
Adjunt. to standard preps levodopa/
benserazide or levodopa/ carbidopa in
Parkinson’s dis. and end-of-dose motor
flucts. that cannot be stabil. on those
combs.
C/I: Hypersens., hep. impair., pts. with
pheochromocyt.
Hist. of (NMS) and/ or non-traum.
rhabdomyol.
Concom.use of entacapone and nonselec.
MAOIs –A and MAOIs-B (e.g.
phenelzine, tranylcypromine).
Concom. use of a selec. MAOIs -A. plus a
sele. MAOIs -B and entacapone.
COMT Inhibitor, Decarboxylase Inhibitor, Dopamine Precursor. Levodopa 50, 75, 100, 125, 150, 200 mg, Carbidopa 12.5, 18.75, 25, 31.25, 37.5, 50 mg, Entacapone 200 mg. F.C. TABS: 30. See lit.
Tmt. Parkinson’s dis., end-of-dose motor
flucts. not stabiliz. on levodopa/dopa
decarboxylase (DCC) inhibit. tmt.
C/I: Hypersens., severe hepat. impair,
narrow-angle glauc., pheochromocyt.,
concom. use with MAO-A and MAO-B
inhibits., prev. history NMS and/or nontraum.
rhabdomyolys., lact.
