Antispasmodic

8 Drugs classified under this drug class

Antispasmodic. Atropine Sulphate 1 mg/ml, 20 mg / 10 ml.
AMPS: 100. 0.4-0.10 mg by I.V. or I.M.
inject. Complete atropiniz. dose: 2mg I.V.
Relax. of spastic GI tract (e.g. pylorospasm),
biliary and GU tracts; reduct. of salivat. and
bronchial secret. combat CNS and periph.
toxic effects; suppress vagally-mediated
bradyarrhythmias.

Antispasmodic. Mebeverine HCl 135 mg.
TABS: 50 x 135 mg. 1 tab. 3 x dly, pref.
bef. meals. When desired effects
achieved, reduce dose grad. Child.
under 10 yrs: Not recommend.
Sympt. tmt. abdom. pain, bloating,
abdom. distent. flatulence, other sympt.
IBS, GI spasm second to organ. dis. as in
diverticulos.
diverticulit., Crohn’s dis.

Antispasmodic. Dicyclomine HCl 10 mg.
TABS.: 20×10 mg. Adolescen. & Adult.> 12 yrs.: 10-20mg×3/d. before / after meals. Child. (2-12 yrs.): 10mg ×3/d.
Max. dly. dose of 40mg.
Adjunct. ther. in irritable bowel syndrome, neurogenic bowel disturbance.
C/I: Hypersens.

Antispasmodic. Oxybutynin (HCl) 5 mg.
Tabs:30: Adlts: one tab 2-3 times per day,
max. daily dosage: 4 tabs.
Childr. above 6 years of age:  2.5 mg. twice/d, max. 3 tabs/d .
tmt. of urinary incontin., urgency, and freq. in the unstable bladder, due to neurogenic bladder disorders (detrusor hyperreflexia) in condits. such as multiple sclerosis and spina bifida, or to idiopathic detrusor instability (motor urge incontin).
In childr. of 5 years of age or older for:
- Urinary incontin., urgency, and freq. in unstable bladder condit. due to idiopathic overact. bladder or neurogenic bladder disorders (detrusor overactivity).
- Noct. enuresis assoc. with detrusor overact., in conjunct. with nondrug ther., when other tmt. has failed

C/I: Hypersens.• MG• Sev. UC
• toxic megacolon
• Narrow angle glauc. or shallow anter. chamber;
• GI obstruct. dis. incl. paralytic ileus, intestinal atony
• bladder outflow obstruct. where urinary retent. may be precipitated

Antispasmodic. Papaverine (HCl) 40, 80 mg.
TABS: 30, 250, 1,000 x 40mg, 80mg. See lit.
Smooth muscle spasm.
C/I: AV block, glaucoma, depress.
myocard. funct.

Antispasmodic. Papaverine (HCl) 40 mg / 2 ml.
AMP: 10 x 2 ml. 30-120 mg. I.M. or I.V (I.V. reserved when immediate effect is desired). Admin. should be slow (1-2 min.).
Antispasmod. in: visceral spasm, G.I. colic, biliary/urin. tract spasms, periph. vasc. dis. with vasospastic element, vasc. spasm assoc. with acute M.I., ang. pect., periph. and pulm. embolism.
C/I: Hypersens. to papaverine. IV inj.: in pts. with complete AV block. Severe HF. Recent MI. Recent heart attack. arrhythmia (bradycardia). In case of intracran. hypertens. Hepatic dis.