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  • Anticoagulant
    7 Drugs classified under this drug class


    All the Drug Class Drugs

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    Apixaban Teva
    Teva
    RX
    partial basket chart
    Multiple ingredients
    Apixaban Teva

    Anticoagulant, Direct Factor Xa Inhibitor. Apixaban 2.5 mg, Apixaban 5 mg.
    FC tabs 2.5mg/5 mg X30
    Prevent. of VTE (VTEp): elect. hip or knee replacem. surgery 2.5 mg taken orally 2Xd, initial dose to be taken 12 to 24 hs after surg. In ptts. undergoing hip replacem., tmt. is 32 to 38 days. In ptts. undergoing knee replacem., tmt. is 10 to 14 days. Prevent. of stroke and syst. embol. in ptts. with non-valv. atrial fibrill. (NVAF): 5 mg taken orally 2Xd. See full prescript. info.
     for 2.5 mg: prevent. of venous thromboemb. events (VTE) in adlt. ptts. who have undergone elect. hip or knee replacem.
     for both 2.5 and 5 mg: prevent. of stroke and syst. embol. in adlt. ptts. with non-valv. atrial fibrill. (NVAF), with one or more risk factors, such as prior stroke or transient isch. attack (TIA); age≥ 75 y; HT; diabetes mellitus; sympt. heart fail. (NYHA Class ≥ II). Tmt. of deep vein thromb.(DVT) and pulmon. embol. (PE), and prevent. of recurrent DVT and PE in adults.

    C/I:
    Hypersens. Act. clin. signif. bleeding. • Hep. dis. assoc. with coagulopathy and clinic. relevant bleeding risk • Lesion or condit. posing a signif. risk factor for major bleeding, incl. current or recent GI ulcerat., presence of malign. neoplasms at high risk of bleeding, recent brain or spinal injury, recent brain, spinal or ophthalmic surg., recent intracran. haemorrhage, known or susp. oesophageal varices, arteriovenous malform., vasc. aneurysms or major intraspinal or intracerebral vasc. abnorm. • Concom. tmt. with any other anticoag. agent e.g. unfraction. heparin (UFH), low MW heparins (enoxaparin, dalteparin, etc.), heparin deriv. (fondaparinux, etc.), oral anticoag. (warfarin, rivaroxaban, dabigatran, etc.) except under spec. circumst. of switching anticoag. ther. or when UFH is given at doses necess. to maintain an open ctral. venous or arterial catheter.

    Arixtra
    Perrigo
    RX
    not in the basket chart
    Arixtra

    Anticoagulant. Fondaparinux (sodium) 2.5 mg/0.5 ml, 0.75 mg/ 0.6 ml.
    PRE-FILLED SYR. (sol., for inject.): 10 x
    0.5 ml x 2.5 mg, 10 x
    0.6 ml x 0.75 mg. See lit.
    Prevent. VTE in pts. undergoing major
    orthoped. surg. lower limbs. Prevent. VTE in
    pts. undergoing abdom. surg. who are at high risk thromboembol. complicats.
    Prevent. VTE in medical pts. at high risk for
    VTE and immobilised due to acute illness
    such as card. insuffic. and/or acute respirat.
    disords, and/or acute infects. or inflamm.
    dis. Tmt. unstable angina or non-ST segm.
    elevat. myocard. infarct. (UA/NSTEMI) in
    pts. where urgent invas. manage. (PCI) not
    indicat. Tmt. ST segm. elevat. myocard.
    infarct. (STEMI) in pts managed with
    thrombolytics or who are not to receive
    other form reperfus. ther.
    C/I: Hypersens., active clin. bleed., acute
    bact. cardit., severe ren. fail. (creatinine
    clear. <20 ml/min).

    Coumadin
    Taro
    RX
    partial basket chart
    Coumadin

    Anticoagulant. Warfarin (sodium) 1, 2, 2.5, 5 mg.
    TABS: 30 x 1 mg, 2 mg,
    2.5 mg, 5 mg. See lit.
    Proph.and/or tmt. ven. thromb. (and its
    extension), pulm. embolism, proph. and/
    or
    tmt. thromb. embol. complicats. assoc.
    with atrial fibrill. and/or card. valve
    replace., reduce risk death, recur. M.I.,
    stroke, system. embol. aft. M.I.
    C/I: Hypersens., pregn., hemorrh., bleed.
    tendencies, blood dyscras., recent/
    complic. surg., threat. abort., eclamps.,
    pre-eclamps.

    Eliquis
    Pfizer
    RX
    partial basket chart
    Eliquis

    Anticoagulant, Direct Factor Xa Inhibitor. Apixaban 2.5 mg, 5 mg.
    F.C. TAB: 60 x 2.5mg, 60 x 5mg
    Preven. of VTE (VTEp): elective hip or
    knee replac. surg.- 2.5 mg ×2/d.
    Init. dose should be taken 12 - 24 hrs.
    after surg.
    In pts. underg. hip replac. surg.- The
    recom. duration of tmt. is 32- 38 d.
    In pts. underg. knee replac. surg.: The
    recom. duration of tmt. is 10- 14 d.
    Preven. of stroke & syst. embol. in pts.
    with non-valvul. atrial fibril. (NVAF):
    5 mg ×2/d.
    Dose reduction: 2.5mg×2/d in pts. with
    NVAF and at least two of the follow.
    characteristics: age ≥ 80 yrs., bdy. wt. ≤
    60 kg, or ser. Cr ≥ 1.5 mg/dL (133
    micromole/L).
    Ther. should be cont. long term.
    Tmt. of DVT, tmt. of PE and preven. of
    recur. DVT &PE (VTEt)
    Tmt. of acute DVT and tmt. of PE is 10
    mg×2/d for the first 7 d. follow. by 5
    mg ×2/d.
    As per avail. med. guidelines, short
    durat. of tmt. (at least 3 mnths.) should
    be based on transient risk factor. (e.g.
    recent surg., trauma, immobilis.).
    Preven. of recur. DVT & PE is 2.5
    mg×2/d. When preven. of recur. DVT &
    PE is indic., the 2.5 mg×2/d should be
    init. follow. complet. of 6 mnths. of tmt.
    5 mg×2/d or with another anticoag.
    See Lit.
    2.5 mg tabs. - Preven. of VTE in adult pts.
    who have undergone elect. hip or knee
    replac. surg.
    Preven. of stroke and syst. embol. in adult
    pts. NVAF, with one/ more risk fact., e.g as
    prior stroke, TIA; age ≥ 75 yrs.; hypertens.;
    diabetes. mell.; symptom. HF (NYHA Class
    ≥ II).
    Tmt. of DVT, PE , and preven. of recur.
    DVT & PE in adult.
    5 mg tabs. - Preven. of stroke, syst. embol.
    in adult pts. NVAF, with one/ more risk
    fact., e.g. prior stroke or TIA; age ≥ 75 yrs.;
    hypertens.; diabetes mell.; symptom. HF
    (NYHA Class ≥ II).
    Tmt. of DVT, PE in adult. 
    C/I: Hypersens.
    Active clinic. signific. bleed.
    Hep. dis. assoc. with coagulopathy
    &clinic. relevant bleed. risk.
    Lesion/ condit. if consid. a signific. risk
    factor for major bleed. This may include
    current or recent GI ulcer., presence of
    malig. neoplasm. at high risk of bleed.,
    recent brain, spinal inj., recent brain,
    spinal or ophthalmic surg., recent
    intracran. haemorrhage, known/
    suspect. esophagi. varices, arterioven.
    malform., vasc. aneurysms or major
    intraspinal or intracerebr. vascular
    abnorm.
    Concom. tmt. with any other anticoag.
    agent e.g. unfraction. heparin (UHF), low
    molec. wt. heparins (enoxaparin,
    dalteparin, etc.), heparin derivat.
    (fondaparinux, etc.), oral anticoag.
    (warfarin, rivaroxaban, dabigatran, etc.)
    except under specific circumstances of
    switching anticoag. ther.or when UHF is
    given at doses necessary to maintain an
    open centr. ven. or arterial catheter.

    Heparin Injection BP 5,000 units/ml
    Pharmalogic
    RX
    partial basket chart
    Heparin Injection BP 5,000 units/ml

    Anticoagulant. Heparin 25,000 IU / 5 ml.
    VIALS: 25 x 5 ml. I.V./S.C.
    See lit.
    Thrombo-embol. disords., proph. deep
    vein thromb., thrombo-embol. events.

    Heparin Sodium ROVI 5,000 IU/ml
    Kamada
    RX
    full basket chart
    Heparin Sodium ROVI 5,000 IU/ml

    Anticoagulant. Heparin Sodium 5000 IU/ml.
    Sol. for inj.:  5 ml vials with 5000 IU/ml See lit..
    Prevent. of thromboembolic dis.
    Part of tmt of venous or arter. thromboemb. dis.
    For anticoag. during tmt or operat. with extracorporeal circ.
    C/I:Hypersens. Ac. or prev. hist. of heparin-induc. allergic thrombocytopenia (type 2). Dis. assoc. with a bleeding diathesis, severe hepatic, renal or pancr. dis.
    Dis. with susp. lesion of the vasc. system, e.g. GI ulcers, hypertension (>105 mmHg diastolic), cerebral haemorrhage, trauma or surgery involving the CNS, eye operat., retinopathies, vitreous haemorrhage, aneurysm of the cerebral arteries, infect. endocard. Threatened miscarriage.  Spinal anaesth, epidural anaesth, lumbar punct.
    Organ lesions assoc. with bleeding tendency.
    Must not be used in preterm or newborn babies because of benzyl alcohol content.

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