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  • Anticoagulant
    6 Drugs classified under this drug class

    All the Drug Class Drugs

    not in the basket chart

    Anticoagulant. Fondaparinux (sodium) 2.5 mg/0.5 ml, 0.75 mg/ 0.6 ml.
    PRE-FILLED SYR. (sol., for inject.): 10 x
    0.5 ml x 2.5 mg, 10 x
    0.6 ml x 0.75 mg. See lit.
    Prevent. VTE in pts. undergoing major
    orthoped. surg. lower limbs. Prevent. VTE in
    pts. undergoing abdom. surg. who are at high risk thromboembol. complicats.
    Prevent. VTE in medical pts. at high risk for
    VTE and immobilised due to acute illness
    such as card. insuffic. and/or acute respirat.
    disords, and/or acute infects. or inflamm.
    dis. Tmt. unstable angina or non-ST segm.
    elevat. myocard. infarct. (UA/NSTEMI) in
    pts. where urgent invas. manage. (PCI) not
    indicat. Tmt. ST segm. elevat. myocard.
    infarct. (STEMI) in pts managed with
    thrombolytics or who are not to receive
    other form reperfus. ther.
    C/I: Hypersens., active clin. bleed., acute
    bact. cardit., severe ren. fail. (creatinine
    clear. <20 ml/min).

    partial basket chart

    Anticoagulant. Warfarin (sodium) 1, 2, 2.5, 5 mg.
    TABS: 30 x 1 mg, 2 mg,
    2.5 mg, 5 mg. See lit.
    Proph.and/or tmt. ven. thromb. (and its
    extension), pulm. embolism, proph. and/
    tmt. thromb. embol. complicats. assoc.
    with atrial fibrill. and/or card. valve
    replace., reduce risk death, recur. M.I.,
    stroke, system. embol. aft. M.I.
    C/I: Hypersens., pregn., hemorrh., bleed.
    tendencies, blood dyscras., recent/
    complic. surg., threat. abort., eclamps.,

    partial basket chart

    Anticoagulant, Direct Factor Xa Inhibitor. Apixaban 2.5 mg, 5 mg.
    F.C. TAB: 60 x 2.5mg, 60 x 5mg
    Preven. of VTE (VTEp): elective hip or
    knee replac. surg.- 2.5 mg ×2/d.
    Init. dose should be taken 12 - 24 hrs.
    after surg.
    In pts. underg. hip replac. surg.- The
    recom. duration of tmt. is 32- 38 d.
    In pts. underg. knee replac. surg.: The
    recom. duration of tmt. is 10- 14 d.
    Preven. of stroke & syst. embol. in pts.
    with non-valvul. atrial fibril. (NVAF):
    5 mg ×2/d.
    Dose reduction: 2.5mg×2/d in pts. with
    NVAF and at least two of the follow.
    characteristics: age ≥ 80 yrs., bdy. wt. ≤
    60 kg, or ser. Cr ≥ 1.5 mg/dL (133
    Ther. should be cont. long term.
    Tmt. of DVT, tmt. of PE and preven. of
    recur. DVT &PE (VTEt)
    Tmt. of acute DVT and tmt. of PE is 10
    mg×2/d for the first 7 d. follow. by 5
    mg ×2/d.
    As per avail. med. guidelines, short
    durat. of tmt. (at least 3 mnths.) should
    be based on transient risk factor. (e.g.
    recent surg., trauma, immobilis.).
    Preven. of recur. DVT & PE is 2.5
    mg×2/d. When preven. of recur. DVT &
    PE is indic., the 2.5 mg×2/d should be
    init. follow. complet. of 6 mnths. of tmt.
    5 mg×2/d or with another anticoag.
    See Lit.
    2.5 mg tabs. - Preven. of VTE in adult pts.
    who have undergone elect. hip or knee
    replac. surg.
    Preven. of stroke and syst. embol. in adult
    pts. NVAF, with one/ more risk fact., e.g as
    prior stroke, TIA; age ≥ 75 yrs.; hypertens.;
    diabetes. mell.; symptom. HF (NYHA Class
    ≥ II).
    Tmt. of DVT, PE , and preven. of recur.
    DVT & PE in adult.
    5 mg tabs. - Preven. of stroke, syst. embol.
    in adult pts. NVAF, with one/ more risk
    fact., e.g. prior stroke or TIA; age ≥ 75 yrs.;
    hypertens.; diabetes mell.; symptom. HF
    (NYHA Class ≥ II).
    Tmt. of DVT, PE in adult. 
    C/I: Hypersens.
    Active clinic. signific. bleed.
    Hep. dis. assoc. with coagulopathy
    &clinic. relevant bleed. risk.
    Lesion/ condit. if consid. a signific. risk
    factor for major bleed. This may include
    current or recent GI ulcer., presence of
    malig. neoplasm. at high risk of bleed.,
    recent brain, spinal inj., recent brain,
    spinal or ophthalmic surg., recent
    intracran. haemorrhage, known/
    suspect. esophagi. varices, arterioven.
    malform., vasc. aneurysms or major
    intraspinal or intracerebr. vascular
    Concom. tmt. with any other anticoag.
    agent e.g. unfraction. heparin (UHF), low
    molec. wt. heparins (enoxaparin,
    dalteparin, etc.), heparin derivat.
    (fondaparinux, etc.), oral anticoag.
    (warfarin, rivaroxaban, dabigatran, etc.)
    except under specific circumstances of
    switching anticoag. ther.or when UHF is
    given at doses necessary to maintain an
    open centr. ven. or arterial catheter.

    Heparin Injection BP 5,000 units/ml
    partial basket chart
    Heparin Injection BP 5,000 units/ml

    Anticoagulant. Heparin 25,000 IU / 5 ml.
    VIALS: 25 x 5 ml. I.V./S.C.
    See lit.
    Thrombo-embol. disords., proph. deep
    vein thromb., thrombo-embol. events.

    Heparin Sodium ROVI 5,000 IU/ml
    full basket chart
    Heparin Sodium ROVI 5,000 IU/ml

    Anticoagulant. Heparin Sodium 5000 IU/ml.
    Sol. for inj.:  5 ml vials with 5000 IU/ml See lit..
    Prevent. of thromboembolic dis.
    Part of tmt of venous or arter. thromboemb. dis.
    For anticoag. during tmt or operat. with extracorporeal circ.
    C/I:Hypersens. Ac. or prev. hist. of heparin-induc. allergic thrombocytopenia (type 2). Dis. assoc. with a bleeding diathesis, severe hepatic, renal or pancr. dis.
    Dis. with susp. lesion of the vasc. system, e.g. GI ulcers, hypertension (>105 mmHg diastolic), cerebral haemorrhage, trauma or surgery involving the CNS, eye operat., retinopathies, vitreous haemorrhage, aneurysm of the cerebral arteries, infect. endocard. Threatened miscarriage.  Spinal anaesth, epidural anaesth, lumbar punct.
    Organ lesions assoc. with bleeding tendency.
    Must not be used in preterm or newborn babies because of benzyl alcohol content.

    Heparin Sodium Teva 25000 IU / 5 ml
    not in the basket chart
    Heparin Sodium Teva 25000 IU / 5 ml

    Anticoagulant. Heparin Sodium 25000 IU / 5 ml.
    VIAL (Sol. for inj./infus.): 1×25000IU/5ml.
    Dosage must be individ.  adjust.
    Prevent. of thromboembol. disord. As part of the tmt. of ven. and arter. thromboembol. disord. (includ.  early tmt. of heart attacks as well as unst. angina. pect.). For the anticoagulant. in case of tmt. or operation with extracorporeal circul. (e.g.heart-lung machine, hemodialysis).
    C/I: Hypersens. Current/ prev. hist. of heparin-induced allergic thrombocytop. (type 2). Disorders assoc.  with a bleed. diathesis, e.g. thrombocytop., coagulopathies, sev. hep./renal/pancreat. disord. Disord. in which there is a suspect. lesion of the vascul. syst., e.g. GI ulc., hypertens. (>105 mm Hg diastolic), cereb. haemorrhage, traum. or surg. operat. involve. the  CNS, eye operat., retinopathies, vitreous  haemorrhage, aneurysm of the cereb. arteries, infect. endocarditis. Threatened miscarriage - Spinal anaesthesia, epid. anaesthesia, lumb. punct. - Organ lesions assoc. with a bleed. tendency. Use in preterm/newborns dueto benzyl alcohol content.