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  • Anticoagulant
    6 Drugs classified under this drug class


    All the Drug Class Drugs

    Arixtra
    Perrigo
    RX
    not in the basket chart
    Arixtra

    Anticoagulant. Fondaparinux (sodium) 2.5 mg/0.5 ml, 0.75 mg/ 0.6 ml.
    PRE-FILLED SYR. (sol., for inject.): 10 x
    0.5 ml x 2.5 mg, 10 x
    0.6 ml x 0.75 mg. See lit.
    Prevent. VTE in pts. undergoing major
    orthoped. surg. lower limbs. Prevent. VTE in
    pts. undergoing abdom. surg. who are at high risk thromboembol. complicats.
    Prevent. VTE in medical pts. at high risk for
    VTE and immobilised due to acute illness
    such as card. insuffic. and/or acute respirat.
    disords, and/or acute infects. or inflamm.
    dis. Tmt. unstable angina or non-ST segm.
    elevat. myocard. infarct. (UA/NSTEMI) in
    pts. where urgent invas. manage. (PCI) not
    indicat. Tmt. ST segm. elevat. myocard.
    infarct. (STEMI) in pts managed with
    thrombolytics or who are not to receive
    other form reperfus. ther.
    C/I: Hypersens., active clin. bleed., acute
    bact. cardit., severe ren. fail. (creatinine
    clear. <20 ml/min).

    Coumadin
    Taro
    RX
    partial basket chart
    Coumadin

    Anticoagulant. Warfarin (sodium) 1, 2, 2.5, 5 mg.
    TABS: 30 x 1 mg, 2 mg,
    2.5 mg, 5 mg. See lit.
    Proph.and/or tmt. ven. thromb. (and its
    extension), pulm. embolism, proph. and/
    or
    tmt. thromb. embol. complicats. assoc.
    with atrial fibrill. and/or card. valve
    replace., reduce risk death, recur. M.I.,
    stroke, system. embol. aft. M.I.
    C/I: Hypersens., pregn., hemorrh., bleed.
    tendencies, blood dyscras., recent/
    complic. surg., threat. abort., eclamps.,
    pre-eclamps.

    Eliquis
    Pfizer
    RX
    partial basket chart
    Eliquis

    Anticoagulant, Direct Factor Xa Inhibitor. Apixaban 2.5 mg, 5 mg.
    F.C. TAB: 60 x 2.5mg, 60 x 5mg
    Preven. of VTE (VTEp): elective hip or
    knee replac. surg.- 2.5 mg ×2/d.
    Init. dose should be taken 12 - 24 hrs.
    after surg.
    In pts. underg. hip replac. surg.- The
    recom. duration of tmt. is 32- 38 d.
    In pts. underg. knee replac. surg.: The
    recom. duration of tmt. is 10- 14 d.
    Preven. of stroke & syst. embol. in pts.
    with non-valvul. atrial fibril. (NVAF):
    5 mg ×2/d.
    Dose reduction: 2.5mg×2/d in pts. with
    NVAF and at least two of the follow.
    characteristics: age ≥ 80 yrs., bdy. wt. ≤
    60 kg, or ser. Cr ≥ 1.5 mg/dL (133
    micromole/L).
    Ther. should be cont. long term.
    Tmt. of DVT, tmt. of PE and preven. of
    recur. DVT &PE (VTEt)
    Tmt. of acute DVT and tmt. of PE is 10
    mg×2/d for the first 7 d. follow. by 5
    mg ×2/d.
    As per avail. med. guidelines, short
    durat. of tmt. (at least 3 mnths.) should
    be based on transient risk factor. (e.g.
    recent surg., trauma, immobilis.).
    Preven. of recur. DVT & PE is 2.5
    mg×2/d. When preven. of recur. DVT &
    PE is indic., the 2.5 mg×2/d should be
    init. follow. complet. of 6 mnths. of tmt.
    5 mg×2/d or with another anticoag.
    See Lit.
    2.5 mg tabs. - Preven. of VTE in adult pts.
    who have undergone elect. hip or knee
    replac. surg.
    Preven. of stroke and syst. embol. in adult
    pts. NVAF, with one/ more risk fact., e.g as
    prior stroke, TIA; age ≥ 75 yrs.; hypertens.;
    diabetes. mell.; symptom. HF (NYHA Class
    ≥ II).
    Tmt. of DVT, PE , and preven. of recur.
    DVT & PE in adult.
    5 mg tabs. - Preven. of stroke, syst. embol.
    in adult pts. NVAF, with one/ more risk
    fact., e.g. prior stroke or TIA; age ≥ 75 yrs.;
    hypertens.; diabetes mell.; symptom. HF
    (NYHA Class ≥ II).
    Tmt. of DVT, PE in adult. 
    C/I: Hypersens.
    Active clinic. signific. bleed.
    Hep. dis. assoc. with coagulopathy
    &clinic. relevant bleed. risk.
    Lesion/ condit. if consid. a signific. risk
    factor for major bleed. This may include
    current or recent GI ulcer., presence of
    malig. neoplasm. at high risk of bleed.,
    recent brain, spinal inj., recent brain,
    spinal or ophthalmic surg., recent
    intracran. haemorrhage, known/
    suspect. esophagi. varices, arterioven.
    malform., vasc. aneurysms or major
    intraspinal or intracerebr. vascular
    abnorm.
    Concom. tmt. with any other anticoag.
    agent e.g. unfraction. heparin (UHF), low
    molec. wt. heparins (enoxaparin,
    dalteparin, etc.), heparin derivat.
    (fondaparinux, etc.), oral anticoag.
    (warfarin, rivaroxaban, dabigatran, etc.)
    except under specific circumstances of
    switching anticoag. ther.or when UHF is
    given at doses necessary to maintain an
    open centr. ven. or arterial catheter.

    Heparin EP Lock Flush Solution
    Kamada
    RX
    full basket chart
    Heparin EP Lock Flush Solution

    Anticoagulant. Heparin Sodium 10 IU/ml, 100 IU/ml.
    SINGLE DOSE VIAL: 10 IU/ml; 100 IU/ml x
    20 x 10 ml. See lit.
    Maint. potency I.V. device. May be used
    foll. initial placement of device in vein or
    aft. withdrawal of blood lab. analysis.
    C/I: Hypersens., severe
    thrombocytopen., uncontrolled active
    bleed. See lit.

    Heparin Injection BP 5,000 units/ml
    Pharmalogic
    RX
    partial basket chart
    Heparin Injection BP 5,000 units/ml

    Anticoagulant. Heparin 25,000 IU / 5 ml.
    VIALS: 25 x 5 ml. I.V./S.C.
    See lit.
    Thrombo-embol. disords., proph. deep
    vein thromb., thrombo-embol. events.

    Heparin Sodium Teva 25000 IU / 5 ml
    Teva
    RX
    not in the basket chart
    Heparin Sodium Teva 25000 IU / 5 ml

    Anticoagulant. Heparin Sodium 25000 IU / 5 ml.
    VIAL (Sol. for inj./infus.): 1×25000IU/5ml.
    Dosage must be individ.  adjust.
    Prevent. of thromboembol. disord. As part of the tmt. of ven. and arter. thromboembol. disord. (includ.  early tmt. of heart attacks as well as unst. angina. pect.). For the anticoagulant. in case of tmt. or operation with extracorporeal circul. (e.g.heart-lung machine, hemodialysis).
    C/I: Hypersens. Current/ prev. hist. of heparin-induced allergic thrombocytop. (type 2). Disorders assoc.  with a bleed. diathesis, e.g. thrombocytop., coagulopathies, sev. hep./renal/pancreat. disord. Disord. in which there is a suspect. lesion of the vascul. syst., e.g. GI ulc., hypertens. (>105 mm Hg diastolic), cereb. haemorrhage, traum. or surg. operat. involve. the  CNS, eye operat., retinopathies, vitreous  haemorrhage, aneurysm of the cereb. arteries, infect. endocarditis. Threatened miscarriage - Spinal anaesthesia, epid. anaesthesia, lumb. punct. - Organ lesions assoc. with a bleed. tendency. Use in preterm/newborns dueto benzyl alcohol content.

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