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  • Sofosbuvir
    3 Drugs classified under this active ingredient


    All the Active Ingredient Drugs

    Epclusa
    Gilead
    RX
    partial basket chart
    Multiple ingredients
    Epclusa

    Antivirals. Sofosbuvir 400 mg, Velpatasvir 100 mg.
    F.C. TABS.: 28. One tab., taken oral., once dly. with or without food. See lit.
    Treatment of chronic hepatitis C virus
    (HCV) infection in adults.
    C/I: Hypersens.
    Meds. that are strong P-gp and/or strong P450 CYP induc.(carbamazepine, phenobarbital, phenytoin, rifampicin, rifabutin and St. John’s wort).

    Harvoni
    Gilead
    RX
    partial basket chart
    Multiple ingredients
    Harvoni

    Antivirals. Ledipasvir 90 mg, Sofosbuvir 400 mg.
    F.C.TABS.:28. Dosage must be ajust. individ. accord. to pt. med. condit. and genotype of the virus.
    Tmt. of chron. hepat. C (CHC) genotype 1, 3 and 4 infect. in adults.
    C/I: Hypersens. Co‑admin. with rosuvastatin. Use with strong P-gp induc.

    Vosevi 400 mg/100 mg/100 mg
    Gilead
    RX
    partial basket chart
    Multiple ingredients
    Vosevi 400 mg/100 mg/100 mg

    Direct-acting Antiviral. Sofosbuvir 400 mg, Velpatasvir 100 mg.
    F.C. TABS.: 28. 1 tab×1/d. with food. Recommen. tmt. durations for all HCV genotypes (DAA: direct-act. antivir. agent)DAA naïve pts. without cirrhosis: 8 wks. DAA naïve pts. with compensat. cirrhosis: 12 wks., 8 wks. may be consid. in genotype 3 infect. pts. DAA experience. pts. without cirrhosis/ with compensat. cirrhosis: 12 wks. See lit.
    Tmt. of chronic HCV infec. in adults.
    C/I: Hypersens. Concom. use with strong P-glycoprotein (P-gp) and/or strong cytochrome P450 (CYP) induc. (e.g. rifampicin, rifabutin, St. John’s wort [Hypericum perforatum], carbamazepine, phenobarbital and phenytoin).
    Concom. use with rosuvastatin or dabigatran etexilate.
    Concom. use with ethinylestradiol-contain. agent. e.g. comb. oral contracept. or contracept. vag. rings.

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