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  • Sofosbuvir
    4 Drugs classified under this active ingredient


    All the Active Ingredient Drugs

    Epclusa
    Gilead
    RX
    partial basket chart
    Multiple ingredients
    Epclusa

    Antivirals. Sofosbuvir 400 mg, Velpatasvir 100 mg.
    F.C. TABS.: 28. One tab., taken oral.,
    once dly. with or without food. See lit.
    Treatment of chronic hepatitis C virus
    (HCV) infection in adults.
    C/I: Hypersens. Use with strong P gp and strong CYP induc.: Med. products that are strong P glycoprotein (P-gp) and/or strong cytoch. P450 (CYP) induc. (carbamazepine, phenobarbital, phenytoin, rifampicin, rifabutin, and St. John’s wort). Co
    admin. will signific. decrease sofosbuvir
    or velpatasvir plasma conc. and could
    result in loss of efficacy of this formul.

    Harvoni
    Gilead
    RX
    partial basket chart
    Multiple ingredients
    Harvoni

    Antivirals. Ledipasvir 90 mg, Sofosbuvir 400 mg.
    F.C.TABS.:28. Dosage must be ajust. individ. accord. to pt. med. condit. and genotype of the virus.
    Tmt. of chron. hepat. C (CHC) genotype 1, 3 and 4 infect. in adults.
    C/I: Hypersens. Co‑admin. with rosuvastatin. Use with strong P-gp induc.

    Sovaldi
    Gilead
    RX
    partial basket chart
    Sovaldi

    Polymerase Inhibitor (Anti-HCV). Sofosbuvir 400 mg.
    TABS.: 28. 400 mg ×1/d with food, should be used in comb. with other medicinal products. See lit.
    Indicated in comb. with other med. products for the tmt. of chronic hepatitis C (CHC) in adults. For HCV genotype specific activity.
    C/I: Hypersens. Med. products that are strong P-gp inducer. (carbamazepine, phenobarbital, phenytoin, rifampicin, St. John's wort). Co-admin. will significantly decrease sofosbuvir plasma conc.

    Vosevi 400 mg/100 mg/100 mg
    Gilead
    RX
    partial basket chart
    Multiple ingredients
    Vosevi 400 mg/100 mg/100 mg

    Direct-acting Antiviral. Sofosbuvir 400 mg, Velpatasvir 100 mg.
    F.C. TABS.: 28. 1 tab×1/d. with food. Recommen. tmt. durations for all HCV genotypes (DAA: direct-act. antivir. agent)DAA naïve pts. without cirrhosis: 8 wks. DAA naïve pts. with compensat. cirrhosis: 12 wks., 8 wks. may be consid. in genotype 3 infect. pts. DAA experience. pts. without cirrhosis/ with compensat. cirrhosis: 12 wks. See lit.
    Tmt. of chronic HCV infec. in adults.
    C/I: Hypersens. Concom. use with strong P-glycoprotein (P-gp) and/or strong cytochrome P450 (CYP) induc. (e.g. rifampicin, rifabutin, St. John’s wort [Hypericum perforatum], carbamazepine, phenobarbital and phenytoin).
    Concom. use with rosuvastatin or dabigatran etexilate.
    Concom. use with ethinylestradiol-contain. agent. e.g. comb. oral contracept. or contracept. vag. rings.

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