All the Active Ingredient Drugs
Antivirals. Sofosbuvir 400 mg, Velpatasvir 100 mg. F.C. TABS.: 28. One tab., taken oral., once dly. with or without food. See lit.
Treatment of chronic hepatitis C virus
(HCV) infection in adults.
C/I: Hypersens.
Meds. that are strong P-gp and/or strong P450 CYP induc.(carbamazepine, phenobarbital, phenytoin, rifampicin, rifabutin and St. John’s wort).
Antivirals. Ledipasvir 90 mg, Sofosbuvir 400 mg. F.C.TABS.:28. Dosage must be ajust. individ. accord. to pt. med. condit. and genotype of the virus.
Tmt. of chron. hepat. C (CHC) genotype 1, 3 and 4 infect. in adults.
C/I: Hypersens. Co‑admin. with rosuvastatin. Use with strong P-gp induc.
Direct-acting Antiviral. Sofosbuvir 400 mg, Velpatasvir 100 mg. F.C. TABS.: 28. 1 tab×1/d. with food. Recommen. tmt. durations for all HCV genotypes (DAA: direct-act. antivir. agent): DAA naïve pts. without cirrhosis: 8 wks. DAA naïve pts. with compensat. cirrhosis: 12 wks., 8 wks. may be consid. in genotype 3 infect. pts. DAA experience. pts. without cirrhosis/ with compensat. cirrhosis: 12 wks. See lit.
Tmt. of chronic HCV infec. in adults.
C/I: Hypersens. Concom. use with strong P-glycoprotein (P-gp) and/or strong cytochrome P450 (CYP) induc. (e.g. rifampicin, rifabutin, St. John’s wort [Hypericum perforatum], carbamazepine, phenobarbital and phenytoin).
Concom. use with rosuvastatin or dabigatran etexilate.
Concom. use with ethinylestradiol-contain. agent. e.g. comb. oral contracept. or contracept. vag. rings.