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  • Direct-acting Antiviral
    2 Drugs classified under this drug class


    All the Drug Class Drugs

    Veklury®
    Gilead
    RX
    not in the basket chart
    Veklury®

    Direct-acting Antiviral. Remdesivir 100 mg.
    VIAL (pwdr.  for concentrate for sol. for infus.):1×100 mg.  1st Day: 200 mg. Day 2nd -5th : 100 mg.
    Tmt. of COVID-19 in adult. &  in adolesc.  (aged 12 -18 yrs. wt. ≥ 40 kg) with pneum. requir.  supplemental oxygen (low- or high-flow oxygen or other non-invas. ventilation at start of tmt.)
    C/I: Hypersens.

     

    Vosevi 400 mg/100 mg/100 mg
    Gilead
    RX
    partial basket chart
    Multiple ingredients
    Vosevi 400 mg/100 mg/100 mg

    Direct-acting Antiviral. Sofosbuvir 400 mg, Velpatasvir 100 mg.
    F.C. TABS.: 28. 1 tab×1/d. with food. Recommen. tmt. durations for all HCV genotypes (DAA: direct-act. antivir. agent)DAA naïve pts. without cirrhosis: 8 wks. DAA naïve pts. with compensat. cirrhosis: 12 wks., 8 wks. may be consid. in genotype 3 infect. pts. DAA experience. pts. without cirrhosis/ with compensat. cirrhosis: 12 wks. See lit.
    Tmt. of chronic HCV infec. in adults.
    C/I: Hypersens. Concom. use with strong P-glycoprotein (P-gp) and/or strong cytochrome P450 (CYP) induc. (e.g. rifampicin, rifabutin, St. John’s wort [Hypericum perforatum], carbamazepine, phenobarbital and phenytoin).
    Concom. use with rosuvastatin or dabigatran etexilate.
    Concom. use with ethinylestradiol-contain. agent. e.g. comb. oral contracept. or contracept. vag. rings.

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