Risperidone

5 Drugs classified under this active ingredient

Atypical Antipsychotic. Risperidone 1, 2, 3, 4 mg, 1 mg/ml.
F.C.TABS: 6, 20 x 1 mg; 20 x 2 mg, 3 mg, 4 mg.
ORAL SOLN: 30 ml x 1 mg/ml.
SCHIZO/PSYCHOT. DIS.: adults. Initial: 1 mg 2 x dly;
may be incr. to 2 mg 2 x dly on 2nd day.
Optim. range: 4-6 mg. dly.
elderly/adolesc.  ( ages 13-17)
Initial: 0.5 mg dly, incr. by 0.5
mg dly. See prescr. info.
BIPOLAR MANIA: adults. Init.: 2 or 3 mg once dly.
may be incr. by 1 mg  dly at intervals of min. 24 hs.
Chld/Adolesc. (10-17). Init. 0.5 mg dly, can be incr.
by 0.5 mg at intervals of min. 24 hs.
Recomm. dose: 2.5 mg dly. See prescr. info.
PSYCH. MANIFEST. OF  DEMENTIA:
Initial: 0.25 mg 2 x dly incr. at 0.25 mg
2x dly accord. to response., every alt.
day. Optim. dose: 0.5 mg 2 x dly.
CONDUCT DISORD.  in > = 50 kg: Starting dose: 0.5 mg
1 x dly. Can adjust individ. by
incr. of 0.5 mg 1 x dly. not more
than every other day. Optim.: 1 mg 1 x
dly. In < 50 kg: Starting dose: 0.25 mg 1 x dly:
Can adjust individ. by incr. of
0.25 mg dly. not more than every other
day. Optim. dose: 0.5 mg 1 x dly. See prescr. info
Schizophrenia managem. and psychot. disord. manif.
Antipsych. efficacy was establ. in short-term (6 to 8-weeks)
contr. trials of schizophr. in- pts.
Maint. clin. improvem. during continuat.
ther. in pts. showing initial response.
Short-term tmt (up to 6 weeks) of persist. aggress. in pts
with mod./sev. Alzheimer’s dement. unrespons. to non-pharmacol.
approach when risk of harm to self or others.
Psychot. manifests. dementia.
Conduct and other disrupt. disords: behav. disord.
expressed by impulse control disord. or
self-alienat.-aggress. or tmt.-req.
behavior. disord. with reduced or
substandard intelligence. Not for child
under 5 yrs. Tmt. of  mania in bipolar disord.
C/I: Hypersens.

Atypical Antipsychotic. Risperidone 25, 37.5, 50 mg.
KIT: Vial + pwdr. for susp. (for inj.);
prefilled syringe cont. 2 ml diluent; 3
needles. Admin. every 2 wks by deep
I.M. gluteal inject. Alt. buttocks. Adults:
25 mg I.M. every 2 wks. Max. dose: 50
mg every 2 wks. Dose increments aft.
min. 4 wks. of prev. dose adjust. See lit.
Elderly (>65 yrs): 25 mg I.M. every 2
wks. See lit. Hepat./ ren. impair: If oral
dose of 2 mg well tolerated: 25 mg I.M.
every 2 wks.
Schizophren, schizoaffect. disord.
Monother. or adjuv. ther. for maint. tmt.
bipolar 1 disord. to delay occur.
moodepisodes.
C/I: Hypersens; pregn. and lact. unless
benefit outweighs risk.

Atypical Antipsychotic. Risperidone 1, 2, 3, 4 mg.
TABS/CAPLETS: 20, 30. Schizophren.:
Once/ twice dly.. Init.: 2 mg dly., may
incr. to 4 mg dly. on 2nd day. Most pts.
will benefit from 4-6 mg dly. In some
pts., a slower titrat. phase and a lower
init. & maint. dose may be appropr.
Doses above 10 mg/d have not been
shown to be superior in efficacy to
lower doses and may cause
extrapyram. sympt. Since the safety of
doses above 16 mg/d has not been
evaluat., doses above this level should
not be used.
Elder. pts.: Init. dose 0.5 mg× 2 /d is
recom. Can be adjust. with 0.5 mg
×2/d increm. to 1-2 mg ×2/d. Adolesc.
13-17 yrs.: Init. recom. dose: 0.5 mg 1 ×
dly. Dos. adjust. at intervals not less
than 24 hours in increments of 0.5 /1
mg/d up to 6 mg/d. Recom. dose: 3
mg/d Pts. experienc. persist. somnol.
may benefit from admin. half the dly.
dose twice dly.. Bipolar mania: Adult.-
Once dly. Init.: 2-3 mg. Dose adjust. at
intervals of not less than 24 hrs., in
increm. of 1 mg dly. Recom. dose
range: 1-6 mg dly. Child. & adolesc.
10-17 yrs.: Init. dose: 0.5 mg ×1/d.
Dose adjust. at intervals not less 24
hrs. in increm. of 0.5/ 1 mg dly. up to 6
mg dly. Recom. dose: 2.5 mg 1 × dly.
No addit. benefit was seen above 2.5
mg/d. Pts. experience. persist. somnol.
may benefit from admin. half the dly.
dose twice dly. Experience is lacking in
bipolar mania in child. less than 10 yrs.
of age. Psychotic manifest. of
dementia: Initial: 0.25 mg × 2/d is
recom. May be individ. adjust. by
increm. of 0.25 mg ×2/d not more freq.
than every other day. Optium dose:
0.5-1 mg ×2/d. Persist. aggres. in
Alzheimer’s dementia: no more than 6
wks. tmt. Conduct/other disruptive
behavior disord. (5-18 yrs. of age): Init. dose ≥ 50 kg: 0.5 mg × 1/d recom. May
adjust. at intervals of not more freq.
than every other day, in increm. of 0.5
mg ×1/d. Up to 1.5 mg dly. Optium
dose: 1 mg × 1/d. Init. dose < 50 kg:
0.25 mg×1/d recom. May adjust at
intervals of not more freq. than every
other day, in increm. of 0.25 mg × 1/d.
up to 0.75mg dly. Optium dose: 0.5 mg
× 1/ d Experience is lacking in child.
aged less than 5 yrs. of age. Pts. with
renal/ hep. impair.: All indicat.: Init.
and consecut. dosing should be
halved, and dose titrat. should be
slower. See lit.
Manage. schizophren., manifest.
psychot. disords. Antipsychotic effic. was
establish.in short-term (6 - 8-wks.)
controledl trials of schizophr. inpatients.
Maint. clin. improve. during continuat.
ther. in pts. showing init. response.
Short-term. tmt. (up to 6 wks.) persist.
aggress. in mod.-sev. Alzheimer’s
dementia unrespons. to nonpharmacolog.
approaches and when
there is a risk of harm to self or others.
Conduct/other disrupt. disords: Tmt.
behav. disords. expressed by impulse
control disords. or self-alienat.-aggress.
or tmt.-req. behavior. disords. with
reduced or substandard intelligence. Not
for child. under 5 yrs. Tmt. mania in
bipolar disord. See lit.
C/I: Hypersens. to risperidone or
ingreds. See lit.

Atypical Antipsychotic. Risperidone 25 mg, 37.5 mg, 50 mg.
Powder + solv. for PR Susp. for IM Inj.Vial 25 mg, 37.5 mg, 50mg
FONT
should be administered every 2 weeks by deep intramuscular (IM) deltoid or gluteal injection
treatment of schizophrenia is 25 mg IM every 2 weeks. monotherapy or adjunctive therapy to lithium or valproate for the maintenance treatment of Bipolar I Disorder is 25 mg IM every 2 weeks. maximum dose should not exceed 50 mg/ 2w
-for tmt. of schizophrenia and schizoaffective disords.
- as monother.for maint. tmt. of bipolar I disord. to delay
occurr. of mood episodes.
- for adjunct. maint. tmt. to delay occurr. of mood episodes in pts. with freq. relapsing bipolar disord.
C/I: Hypersensitivity reactions, including anaphylactic reactions and angioedema, have been reported in patients treated with risperidone

Atypical Antipsychotic. Risperidone 1 mg, 2 mg, 3 mg, 4 mg, 1mg/ml.
TABS: 20.
ORAL SOLN: 30 ml x 1 mg/ml. Schizo/
psycho dis: Initial: 1 mg 2 x dly incr. to 2
mg 2 x dly on 2nd day, to 3 mg 2 x dly
on 3rd day. Opt. dose: 2-3 mg 2 x dly or
4-6 mg 1 x dly. Further titrat.: 1-2 mg
incr. at least at wkly intervals.
Ren./ hepat. impair./ elderly/ debil:
Initial: 0.5 mg 2 x dly incr. by 0.5 mg 2 x
dly. Incr. above 1.5 mg 2 x dly only at
least at wkly intervals. Switch to 1 x dly
only aft. 2-3 days at b.i.d. target
regimen.
Psych. manifest dementia: Initial: 0.25
mg 2 x dly incr. at 0.25 mg 2 x dly
accord. to response., every alt. day.
Opt. dose: 0.5 mg 2 x dly.
Conduct disord. > 50 kg: Starting dose:
0.5 mg 1 x dly. Can adjust individ. by
increments of 0.5 mg 1 x dly. not more
than every other day. Max: 1 mg 1 x
dly. Some pts. may req. 1.5 mg 1 x dly.
< 50 kg: Starting dose: 0.25 mg 1 x dly:
Can adjust individ. by increments of
0.5 mg dly not more than every other
day. Max: 0.5 mg 1 x dly. Some pts. may
req. 0.75 mg 1 x dly.
Manag. of schizoph. & manifest. of
psychot. disord. The antipsychot. effic. of
Risperidone was establish. in short-term
(6 to 8-wks.) control. trials of schizoph.
inpatients. Maintain. the clinic. improve.
during contin. ther. in pts. who have
shown an init. tmt. response. Short-term
tmt. (up to 6 wks.) of persist. aggres. in
pts. with moder.- sev. Alzheimer’s
dementia unrespons. to nonpharmacolog.
approaches and when
there is a risk of harm to self/others.
Conduct & other disrupt. disord.: Tmt. of
behave. disord. expres. by impulse control
disord. or self-alienated-aggres. or tmt.-
requir. behave. disord. with reduced or
substandard intelligence. Tmt. should not
be given to child. <5 yrs.
Tmt. of mania in bipol. disord. These
episodes are character. by sympt. such as
elevated, expans. or irritable mood, inflat.
self-esteem, decre. need for sleep,
pressured speech, racing thoughts,
distractibility, or poor judgment, includ.
disruptive or aggres. behav.
C/I: Hypersens.