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  • Pirfenidone
    3 Drugs classified under this active ingredient


    All the Active Ingredient Drugs

    Esbriet 267 mg
    Roche
    RX
    partial basket chart
    Esbriet 267 mg

    Immunosuppressant. Pirfenidone 267 mg.
    HARD CAPS.: 252, 270. The recom. dly.
    dose is 801 mg(3 caps.) × 3/d with food
    for a total of 2403 mg/day. See lit.
    Tmt. of mild to moder. idiop. pulmon.
    fibrosis in adult.
    C/I: Hypersens. Hist.of angioed. with
    pirfenidone. Concom. use of fluvoxamine. Sev. hep. impair. or end stage liver dis. Sev. renal impair.(CrCl <30 ml/min) or end stage
    renal dis. requir. dialysis.

    Piron
    Unipharm Trading Ltd
    RX
    not in the basket chart
    Multiple ingredients
    Piron

    Antifibrinolytic. Pirfenidone 267 mg, Pirfenidone 801 mg.
    FC tab: 267/801 mg X 90
     Dose to be titr. to 2403 mg/d over a 14-day period as follows:
    ● Days 1 to 7: a dose of 267 mg admin. 3/d (801 mg/d)
    ● Days 8 to 14: a dose of 534 mg admin. 3/d (1602 mg/d)
    ● Day 15 onward: a dose of 801 mg admin. 3/d (2403 mg/d)
    maint. dly. dose is 801 mg 3/d with food (total of 2403 mg/d). Doses above 2403 mg/d are not recomm. for any ptt. See lit.
    In adlts. for mild to moder. idiopathic pulmon. fibrosis (IPF).
    C/I:  Hypersens. Hist. of angioedema with this drug.
    Concom. use of fluvoxamine
    Sev. hepatic impairm. or end stage liver dis.
    Sev. renal impairm. (CrCl <30 ml/min) or end stage renal dis. req. dialysis

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