Pirfenidone

3 Drugs classified under this active ingredient

Immunosuppressant. Pirfenidone 267 mg.
HARD CAPS.: 252, 270. The recom. dly.
dose is 801 mg(3 caps.) × 3/d with food
for a total of 2403 mg/day. See lit.
Tmt. of mild to moder. idiop. pulmon.
fibrosis in adult.
C/I: Hypersens. Hist.of angioed. with
pirfenidone. Concom. use of fluvoxamine. Sev. hep. impair. or end stage liver dis. Sev. renal impair.(CrCl <30 ml/min) or end stage
renal dis. requir. dialysis.

Immunosuppressant. Pirfenidone 801 mg.

Antifibrinolytic. Pirfenidone 267 mg, Pirfenidone 801 mg.
FC tab: 267/801 mg X 90
 Dose to be titr. to 2403 mg/d over a 14-day period as follows:
● Days 1 to 7: a dose of 267 mg admin. 3/d (801 mg/d)
● Days 8 to 14: a dose of 534 mg admin. 3/d (1602 mg/d)
● Day 15 onward: a dose of 801 mg admin. 3/d (2403 mg/d)
maint. dly. dose is 801 mg 3/d with food (total of 2403 mg/d). Doses above 2403 mg/d are not recomm. for any ptt. See lit.
In adlts. for mild to moder. idiopathic pulmon. fibrosis (IPF).
C/I:  Hypersens. Hist. of angioedema with this drug.
Concom. use of fluvoxamine
Sev. hepatic impairm. or end stage liver dis.
Sev. renal impairm. (CrCl <30 ml/min) or end stage renal dis. req. dialysis