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  • Phenytoin Sodium
    2 Drugs classified under this active ingredient


    All the Active Ingredient Drugs

    Dilantin 125
    Pfizer
    RX
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    Dilantin 125

    Anticonvulsant. Phenytoin Sodium 125 mg/5 ml.
    SUSP: 237 ML
    Dosage should be individualiz. to provide max. benefit. In some cases serum blood level determinat.may be necessary for optimal dosage adjust.—the clinically effect. serum level is usually 10–20 mcg/mL although some mild cases of tonic-clonic (grand mal) epilepsy may be control. with lower serum levels of phenytoin. Adult.: Pts who have received no prev. tmt. may be started 5ml×3/d, and the dose is then adjust. to suit individ. requirem. An incr. to 25ml dly. (625mg), may be made, if necessary.
    An oral load. dose may be used for non-emergency init. of ther. in adult. who require rapid steady state serum levels, and for whom IV  admin. is not desirable. This dosing regimen should be reserved for pts. in a clinic/hospital setting where phenytoin serum levels can be closely monitor.Pts. with a history of renal or hep. dis. should not receive the oral load. dose regimen.
    The recomm. oral load. dose is 1 gr of phenytoin divid.  into three doses (400, 300, 300 mg) and admin. at two hour interv. Normal mainten. dosage is then instituted 24 hrs. after the load. dose, with frequent serum level determinations.
    Elder. Pts.: Phenytoin clearance is decreased slightly in elderly pts. and lower or less freq. dosing may be require.
    Ped.: Init., 5 mg/kg/day in two or three equally divid. doses, with subseq. dosage individual.to a max. of 300 mg dly. A recomm. dly. mainten. dosage is usually 4- 8 mg/kg. Child. over 6 yrs. and adolescents may require the minim.adult dose (300 mg/d.). See lit.
    For the control of tonic clonic (Grand- mal) and psychomotor (Temporal lobe seizures).
    C/I:
    History of hypersens. to phenytoin
    A history of prior acute hepatotox. attributable to phenytoin.
    Coadmin. with delavirdine because of the potent. for loss of virologic response and possible resistance to delavirdine or to the class of non-nucleoside reverse transcriptase inhib.

     

    Epanutin
    Pfizer
    RX
    full basket chart
    Epanutin

    Anticonvulsant. Phenytoin Sodium 100 mg.
    CAPS: 100.
    Adult.: Divid. dly. dosage: For oral caps., pts. who have received no prev.tmt. may be init. on 300 mg dly., to be taken in three equal. divid. doses, and the dosage then adjust. to suit individ. requir. For most adult., the satisfactory mainten. dosage will be 300 mg- 400 mg dly., to be taken in three -four equal. divid. doses respectiv. An incr. up to 600mg dly. may be made if necessary.
    Non-emergency oral load. dose in adult pts.:  An oral load. dose may be used for non-emergen. initiat. of ther. in adult. who require rapid stead. state serum levels, and for whom IV admin. is not desirable. This dosing regimen should be reserved for pts. in a clinic or hospital setting where serum levels can be closely monitor.
    Pts. with a hist. of renal / hep. dis. should not receive the oral load. dose regimen.
    The recomm. oral load. dose is 1 gr  divid. into three doses (400 mg, 300 mg, 300 mg) and admin. at two-hour intervals. Normal mainten. dosage is then instituted 24 hrs. after the load.  dose, with freq. serum level determinat.
    Ped. pts.
    For oral caps., init., 5 mg/kg/d in two / three equal. divid. doses with subsequent dosage individualiz. to a max. of 300 mg dly. A recomm. dly. maintenan. dosage is usually 4 to 8 mg/kg.
    Child. over 6 yrs. and adolesc. may requir. the min. adult dose (300 mg/d). If the daily dosage cannot be divid.equally, the larger dose should be given at bdtme.

    See lit.
    Tmt. of epilepsy.
    C/I: A hist. of hypersens. phenytoin (Reac. have includ. angioedema).
    A history of prior acute hepatotox. attributab.to phenytoin .
    Coadmin. with delavirdine. See lit.

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