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  • Isotretinoin
    2 Drugs classified under this active ingredient

    All the Active Ingredient Drugs

    not in the basket chart

    Retinoid. Isotretinoin 5, 10, 20, 30, 40 mg.
    SOFT CAPS: 30, 60. See lit.
    Severe recalcitrant nodular acne.
    C/I: Pregn., lact., hepat. and renal
    insuffic., hypervit. A, excess. elevated
    blood lipid, hypersens. Not to be taken
    with tetracycl.

    not in the basket chart

    Retinoid. Isotretinoin 5 mg, 10 mg, 20 mg, 40 mg.
    Soft gel caps 30 X 5/10/20/40 mg
    Capsules to be taken with food 1 once or twice /d. Adults and adolescents>12:Start at a dose of 0.5 mg/kg dly. Adjust dose indiv. For most pts., from 0.5-1.0 mg/kg/d. Long-term remission and relapse rates are more closely rel. to total dose admin. than to either duration of tmt. or dly. dose. No substant. addit. benefit to be expected beyond a cumulative dose of 120-150 mg/kg. Duration of tmt. will depend on dly. dose. A tmt. course of 16-24 weeks is normally suffic. to achieve remission. In the majority of pts., complete clearing of acne is obtained with a sgle. course. In the event of a definite relapse at least 8 weeks after discontinuat., a further course may be considered using same dly. and cumulative dose.
    For the tmt. of sev. cystic acne that does not respond to other tmt.
    Pregn. or breastf.
    Women of childbearing potent. unless all of the condit. of the Pregn. Prevent. Progr.are met. Teratogenic
    • hepatic insuffic.
    • excess. elev. blood lipid values
    • hypervitaminosis A
    • concomitant treatment with tetracyclines