All the Active Ingredient Drugs
Sphingosine 1-Phosphate Receptor Modulator. Fingolimod 0.5 mg. CAPS.:28. 0.5 mg ×1/d.
Tmt. of pts. with relaps. forms of multiple sclerosis ( MS ) to reduce the frequency of clin. exacerb. and to delay the accumul. of physic. disability.
C/I: Hypersens. Pts. who have suffered from MI in past 6 mnths. prior initiat. of ther., unstab. angin., stroke or TIA, decompens. heart fail. that required hospitaliz. or class III or IV heart fail. Pts. with high-degree AV block or sick sinus syndr., unless they have function. pacemaker. Pts. with a baseline QTc interv. ≥ 500 ms. Concom. use with Class Ia or Class III anti-arrhyth. meds.
Immunomodulator. Fingolimod HCl 0.5 mg. HARD CAPS.: 7, 28. For init. ther: See lit.
Recommend. dose: 0.5 mg ×1/d.
Tmt. relaps. forms multiple sclerosis (MS).
Reduct. freq. clin. exacerbat., delay
accumul. phys. disabil.
C/I: Pts. who in the last 6 mths. experien.
MI, unst. angina, stroke, TIA, decompen.
heart fail. requiring hospital. or Class III/
IV heart fail. Hist. or presence of Mobitz
Type II 2nd –degr. or 3rd –degr. AV block
or sick sinus synd., unless pt. has a
function. Pacemaker Baseline QTc inter.
≥500 ms. Tmt. with Class Ia or Class III
anti-arrhythm. drugs., hypersens.
