All the Active Ingredient Drugs
Lincosamide. Clindamycin Phosphate 150 mg/ml. AMPS: 5 x 4 ml (600 mg/4 ml). I.M./I.V:
Serious infects: 600-1,200 mg/day in
2-4 eq. doses. More severe anaerob.
infects: 1,200-2,700 mg/day in 2-4 eq.
doses. Life-threat. infects: Up to 4,800
mg/day I.V. Child: 1 mth-16 yrs: 20-40
mg/kg/day in 3-4 eq. doses I.M. Single
dose not to exceed 600 mg.
Serious infects. caused by suscept.
anerobic bact. and suspect. strains of
streptococci, pneumococci and
staphylococci.
Lincosamide. Clindamycin Phosphate 150 mg/ml. Vial: sol for inject / infus 10 X 2 ml/4ml
To be diluted prior to IV admin. and infused over at least 10-60 minutes.
Adlts: Serious infect.: 600 mg - 1.2 g/d in 2/3/4 equal doses.
More sev. infect.: 1.2-2.7 g/d in 2/3/4 equal doses.
Single IM inject. of more than 600 mg are not recomm. nor is admin. of more than 1.2 g in a sgle one-hour infus.
For more serious infect., these doses may have to be incr. In life-threatening situations, doses as high as 4.8 g/d have been given IV to adlts.
Alternatively, may be admin. in the form of a sgle rapid infus. of the first dose followed by continuous IV infus.
Paed. pop:. Childr > 1 month of age): Serious infect: 15-25 mg/kg/d in 3 or 4 equal doses. To be dosed based on total BW regardless of obesity.
More sev. infect.: 25-40 mg/kg/d in 3 or 4 equal doses. In sev. infect. it is recommen. that childr. be given no less than 300 mg/d regardless of BW.
For the tmt.of infections caused by susceptible anaerobic bacteria.
Clindamycin does not penetrate the blood/brain barrier in therapeut. effective qtities
C/I: Hypersens. incl. to lincomycin.
Lincosamide. Clindamycin Phosphate 150 mg/ml. VIAL:150 mg/ml. 1 X 600 mg/4 ml. Adlts: from 600 to 4800 mg/day div. in 2-4 doses. Chldr (>1 month): Serious infec.: 15-25 mg/kg/day in 3-4 equal doses.
Should be dosed based on tot. body wt. regardless of obesity.
Severe infect.: 25-40 mg/kg/day in 3-4 equal doses. In severe infections it is recommended that children be given no less than 300 mg/day regardless of body weight. See lit.
Tmt. of infec. caused by suscept. anaerobic bacteria.
C/I: History of hypersens. to preparations contain. clindamycin or lincomycin. Sol. for inj. must not be given to premature babies or neonates because of the benzyl alcohol content.
Lincosamide. Clindamycin Phosphate 100 mg. OVULES + APPLIC: 3. 1 ovule intravag.
at bedt. for 3 consec. days.
3-day tmt. bact. vaginosis. in non-pregn.
women.
C/I: Hypersens. to clindamycin/lincomycin,
reg. enterit; ulcerat. colit;
history of “antibiotic - assoc.” colit.
Lincosamide. Clindamycin Phosphate 2%. VAG. CREAM: 40 g plus 7 applic. 1
applic. intravag. at bedt. for 7 consec.
days.
Tmt. of bact. vaginos. only if bacteria susceptible to clindamycin were found.
C/I: Pts. with a hist. of hypersens.
to clindamycin, lincomycin.
Pts. with a hist. of IBD or a hist. of antibiotic-associated colitis.
Benzoyl Peroxide 5%, Clindamycin Phosphate 1%. GEL: 25 g. Adults, adolesc: Apply 1 x dly
in even., max. 12 wks. Child: Safety not
establ. under 12 yrs.
Mild-mod. acne vulgaris, partic. inflam.
lesions.
C/I: Hypersens.