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  • DEFERASIROX TARO
    / Taro International Ltd


    Active Ingredient
    Deferasirox 125/250/500 mg

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Dispersible Tablet

    30 X 125 mg

    partial basket chart 37632 4832

    Dispersible Tablet

    30 X 250 mg

    partial basket chart 37633 4833

    Dispersible Tablet

    30 X 500 mg

    partial basket chart 37634 4835

    Related information


    Dosage

    For patients > 2 years old:
    For patients regularly receiving blood transfusions – 20 mg per kilogram body weight.
    For patients who do not regularly receive blood transfusions – 10 mg per kilogram body weight
    The maximum daily dosage is:
    • 40 mg per kilogram body weight for patients regularly receiving blood transfusions.
    • 20 mg per kilogram body weight for adult patients not regularly receiving blood transfusions.
    • 10 mg per kilogram body weight for children aged under 18 years not regularly receiving blood transfusions
    Please refer to the license holder for further details.


    Indications

    Treatment of chronic iron overload due to blood transfusions (transfusional haemosiderosis) in adult and pediatric patients (aged 2 years and over). Also indicated for the treatment of chronic iron overload in patients with non–transfusion-dependent thalassemia syndromes aged 10 years and older. Chelation therapy should only be initiated when there is evidence of iron overload (liver iron concentration [LIC]≥5 mg Fe/g dry weight [dw] or serum ferritin consistently >800 μg/l). LIC is the preferred method of iron overload determination and should be used wherever available


    Contra-Indications

    * Hypersensitivity
    * Moderate or severe kidney disease
    * Concomitant use of another chelating agent


    Special Precautions

    Please refer to the license holder for further details.


    Side Effects

    Please refer to the license holder for further details.


    Drug interactions

    Please refer to the license holder for further details.


    Pregnancy and Lactation

    Please refer to the license holder for further details.


    Overdose

    Please refer to the license holder for further details.


    Manufacturer
    SUN Pharmaceutical Industries LTD., India

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