Astra Zeneca (Israel) Ltd

Aromatase Inhibitor. Anastrozole 1 mg.
TABS: 28. Adults and elderly: 1 tab. dly.
Advanced breast cancer in post-menopaus.
women. Adjuv. tmt of
postmenopaus. women with hormone
receptor-positive early invasive breast
cancer. Adjuv. tmt. early breast cancer in
hormone receptor +tive postmenopaus.
women who have received 2-3 yrs.
adjunct. tamoxifen.
C/I: Severe ren. impair., mod. or severe
hepat. dis., pregn., lact.

Angiotensin II Antagonist. Candesartan Cilexetil 4 mg, 8 mg, 16 mg.
TABS: 28 x 8 mg, 16 mg. Initial: 8 or 16
mg 1 x dly. Maint: 8 or 16 mg 1 x dly,
with or without food. Max. effect: 4
wks.
Hypertens.
C/I: Hypersens., pregn., lact.

Angiotensin II Antagonist, Diuretics. Candesartan Cilexetil 16 mg, Hydrochlorothiazide 12.5 mg.
TABS: 28. 1 tab x dly with or without
food. Elderly: No special dosage. Use
in pts with impair. ren. fusal: see lit.
Not recommend. for child.
Antihypertens. effect usually attained
within 4 wks.
Essent. hypertens. where monother. with
candesartan cilexetil or HCTZ is not
suffic.
C/I: Hypersens., severe ren. impair.,
severe hepat. impair and / or cholestas.,
gout.

Antiplatelet Agent. Ticagrelor 60 mg, 90 mg.
F.C. TABS: 56, 168. With/out food. Initial.
load. dose: 180 mg (2 tabs) dly cont.
with ASA 75-150 mg dly. Maint: 90 mg
2 x dly. Avoid lapses/discont. ther. due
to poss. risk CV/MI. See lit.
Co-admin. with ASA for prevent.
atherothrombot. events in pts. with Acute
Coronary Syndromes (unstable ang., non
ST elevat. MI (NSTEMI) or ST elevat. MI
(STEMI), pts. managed with PCI/CABG).
C/I: Hypersens., active path. bleed.,
history intracran. hemorrh., med-severe
hepat. impair., co-admin. with strong
CYP3A4 inhibs. See lit.

Corticosteroid. Budesonide 0.5 mg.
INHAL. SUSP: 20 (single dose). Initial: 1-2
mg, total dly dose. Child: 6 mths and
older: 0.25-0.5 mg total dly dose. Pts
on oral gluco-corticosteroids: Higher
start. dose: 1 mg total dly dose. Maint:
Titrate to lowest effect. dose: Range:
0.5-4 mg total dly dose. Severe cases:
May incr. further. Child 6 mths and
older: 0.25-2 mg total dly dose. Admin.
1-2 x dly.
Bronch. asth. when other ther. unsuit. or
insuffic.

Corticosteroid. Budesonide 1 mg.
INHAL. SUSP: 20 (single dose). Initial: 1-2
mg, total dly dose. Child: 6 mths and
older: 0.25-0.5 mg total dly dose. Pts
on oral gluco-corticosteroids: Higher
start. dose: 1 mg total dly dose. Maint:
Titrate to lowest effect. dose: Range:
0.5-4 mg total dly dose. Severe cases:
May incr. further. Child 6 mths and
older: 0.25-2 mg total dly dose. Admin.
1-2 x dly.
Bronch. asth. when other ther. unsuit. or
insuffic.