A.M.I. MEDICAL TECHNOLOGIES LIMITED, ISRAEL

Retinoid. Adapalene 1 mg, Benzoyl Peroxide 25 mg.
TUBE (gel): 15, 30, 60 g.
PUMP (gel): 15, 30, 45, 60 g.
Should be appl. to the entire acne affected areas once a day in the eve. on a clean and dry skin. A thin film of gel should be appl. with the fingertips, avoid. the eyes and lips.
If irritat. occurs, the pt. should be directed to apply non-comedogenic moisturizers, to use the medic. less frequent. (e.g. every other day), to suspend use temporarily, or to discont. use altogether.
The duration of tmt. should be determin. by the doctor on the basis of the clinic. condition. Early signs of clinical improve. usually appear after 1-4 wks. of tmt.
The safety and effectiv. not been stud. in child. below 9 yrs. of age.
Cutaneous tmt. of Acne vulgaris when comedones, papules & pustules are present.
C/I: Hypersens.

Retinoid. Adapalene 0.3% w/w, Benzoyl Peroxide 2.5% w/w.
GEL; 15/30/60 g
To be applied once/d in the evening to affected areas of face
and trunk on a clean and dry skin.
Durat. of tmt. to be based on clin. condit. and resp. to tmt.
Early signs of  improvem. usually appear after 1 to 4 weeks.
If no improvem. is seen after 4-8 weeks, reconsider. Not tested in chldr. younger than 12 years.
Tmt. of mod. to sev. acne vulgaris with comedones and numerous
papules and pustules.
C/I: pregn. or planning, hypersens.