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  • Simvacor
    / Unipharm


    Active Ingredient
    Simvastatin 10, 20, 40, 80 mg

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Film Coated Tablets

    30 X 10 mg

    partial basket chart 2764 19432

    Film Coated Tablets

    30 X 20 mg

    partial basket chart 2765 19433

    Film Coated Tablets

    30 X 40 mg

    partial basket chart 27410 19437

    Film Coated Tablets

    30 X 80 mg

    not in the basket chart 4394 19450

    Related information


    Dosage

    See prescribing information for full details.


    Indications

    In patients with coronary heart disease and hypercholesterolemia to: reduce the risk of total mortality by reducing coronary death; reduce the risk of non-fatal myocardial infarcation; reduce the risk for undergoing myocardial revascularization procedures; reduce the risk of stroke and transient ischemic attacks (TIA)., hyperlipidemia. Also indicated as an adjunct to diet to reduce elevated TOTAL-C, LDL-C, Apo B and TG, and to increase HDL-C in patients with primary hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia (Frederickson types 11a and 11b) by lowering the LDL-C/HDL-C and the total C/HDL-C ratios. In homozygous familial hypercholesterolemia as an adjunct to diet and other non-dietary measures in reducing elevated total cholesterol, LDL-cholesterol and apolipoprotein B in patients with homozygous familial hypercholesterolemia when response to these measures is inadequate. Hypertriglyceridemia (Fredrickson type IV hyperlipidemia): for the treatment of patients with primary dysbetalipoproteinemia (Fredrickson type III hyperlipdemia).


    Contra-Indications

    Hypersensitivity to component, active liver disease, unexplained persisting elevated serum transaminases, pregnancy, lactation, concomitant therapy with tetralol class calcium channel blocker. Not recommended in patients under 20 years.


    Special Precautions

    See prescribing information for full details.


    Side Effects

    Generally well tolerated. Abdominal pain, constipation, flatulence, nausea, dyspepsia, headache, diarrhea, fatigue, rash, insomnia and hepatitis.


    Manufacturer
    Trima Israel Pharmaceutical Products Maabarot Ltd. Israel

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