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    / Dexcel


    Active Ingredient
    Alfacalcidol 0.25 mcg

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Capsules

    10, 30, 100

    full basket chart

    Dosage

    See prescribing information for full details.


    Indications

    Renal bone disease, hypothyroidism, rickets and osteomalacia, osteoporosis, primary and tertiary hyperparathyroidism, neonatal hypocalcemia.


    Contra-Indications

    Not to be administered in the presence of plasma calcium levels above 10.8 mg/dl. Evidence of vitamin D toxicity or known hypersensitivity to the effects of vitamin D or any of its analogs.


    Special Precautions

    The intestinal absorption of calcium and phosphate. Serum levels, should be monitored, particularly in patients with renal failure. Should only be prescribed when suitable facilities are available for monitoring calcium levels, renal function and other appropriate biochemical paramenters on a regular basis.


    Side Effects

    Generally relate to hypercalcemia and, in the case of renal impairment, hyperphosphatemia which may be induced by alfacalcidol therapy.


    Drug interactions

    Anticonvulsants, barbiturates, rifampicin. Danazol, digitalis. Mineral oils, cholestyramine, colestipol, sucralfate, aluminum-based antacids. Calcium-containing preparations, thiazides. Magnesium-based antacids, laxatives. Vitamin D or its analogs.


    Manufacturer
    LEO Pharmaceutical Products Ltd.
    Licence holder
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