Presentation and Status in Health Basket
| Presentation | Basket | Yarpa | Pharmasoft |
|---|---|---|---|
|
Capsules 10, 30, 100 |
|
Dosage
See prescribing information for full details.
Indications
Renal bone disease, hypothyroidism, rickets and osteomalacia, osteoporosis, primary and tertiary hyperparathyroidism, neonatal hypocalcemia.
Contra-Indications
Not to be administered in the presence of plasma calcium levels above 10.8 mg/dl. Evidence of vitamin D toxicity or known hypersensitivity to the effects of vitamin D or any of its analogs.
Special Precautions
The intestinal absorption of calcium and phosphate. Serum levels, should be monitored, particularly in patients with renal failure. Should only be prescribed when suitable facilities are available for monitoring calcium levels, renal function and other appropriate biochemical paramenters on a regular basis.
Side Effects
Generally relate to hypercalcemia and, in the case of renal impairment, hyperphosphatemia which may be induced by alfacalcidol therapy.
Drug interactions
Anticonvulsants, barbiturates, rifampicin. Danazol, digitalis. Mineral oils, cholestyramine, colestipol, sucralfate, aluminum-based antacids. Calcium-containing preparations, thiazides. Magnesium-based antacids, laxatives. Vitamin D or its analogs.
