Notensyl

/ CTS

Route of administration: Oral
Adolescents and Adults (above 12 years): 10-20mg three times daily before or after meals.
Children (2-12 years): 10mg three times daily.
Do not exceed a daily dose of 40mg.

Adjunctive therapy in irritable bowel syndrome, neurogenic bowel disturbance.

Hypersensitivity to the active substance or to any of the excipients.

Products containing dicyclomine hydrochloride should be used with caution in any patient with or suspected of having glaucoma or prostatic hypertrophy.
Use with care in patients with hiatus hernia associated with reflux oesophagitis because anticholinergic drugs may aggravate the condition.
Notensyl Tablets contain lactose. Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucosegalactose malabsorption should not take this medicine.

Side-effects seldom occur with dicyclomine. However, in susceptible individuals, dry mouth, thirst and dizziness may occur. On rare occasions, fatigue, sedation, blurred vision, rash, constipation, anorexia, nausea and vomiting, headache and dysuria have also been reported.

None stated.

Pregnancy: Epidemiological studies in pregnant women with products containing dicyclomine hydrochloride (at doses up to 40mg/day) have not shown that dicyclomine hydrochloride increases the risk of foetal abnormalities if administered during the first trimester of pregnancy.
Reproduction studies have been performed in rats and rabbits at doses of up to 100 times the maximum recommended dose (based on 60mg per day for an adult person) and have revealed no evidence of impaired fertility or harm to the foetus due to dicyclomine. Since the risk of teratogenicity cannot be excluded with absolute certainty for any product, the drug should be used during pregnancy only if clearly needed.
Lactation: It is not known whether dicyclomine is secreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when dicyclomine is administered to a nursing mother.

Symptoms of dicyclomine overdosage are headache, dizziness, nausea, dry mouth, difficulty in swallowing, dilated pupils and hot dry skin. Treatment may include emetics, gastric lavage and symptomatic therapy if indicated.

Driving and operating machinery
Patients may experience dizziness, tiredness, sleepiness, or blurred vision during treatment. In such cases, patients should  not drive or operate heavy
machinery.
Children should be cautioned against riding a bicycle or playing near a road etc.