• Home
  • A-B index
  • Pharmacological Index
  • Drug Classes
  • Active Ingredients
  • Companies
  • News
  • Glucose 5% IV Infusion BP
    / Teva


    Active Ingredient

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Solution for Infusion

    50 ml (Viaflo container)

    partial basket chart 42624 7895

    Solution for Infusion

    100 ml (Viaflo container)

    partial basket chart 42625 7896

    Solution for Infusion

    500 ml (Viaflo container)

    partial basket chart 42634 7897

    Dosage

    Adults, the Elderly and Children: The concentration and dosage of glucose solution for intravenous use is determined by several factors including the age, weight, and clinical condition of the patient. Serum-glucose concentrations may
    need to be carefully monitored.
    The recommended dosage for treatment of carbohydrate and fluid depletion is:
    – for adults: 500 ml to 3 litres / 24h
    – for babies and children
    – 0-10 kg body weight: 100 ml/kg/24 h.
    – 10-20 kg body weight: 1000 ml + 50 ml /kg over 10 kg / 24 h.
    – > 20 kg body weight: 1500 ml + 20 ml / kg over 20 kg / 24 h.
    The infusion rate depends on the patient’s clinical condition.
    Infusion rate should not exceed the patient’s glucose oxidation capacities in order to avoid hyperglycaemia. Therefore, the maximum dose ranges from 5mg/kg/min for adults to 10-18 mg/kg/min for babies and children depending on the age and the total body mass.
    The recommended dosage when used as a vehicle or diluent ranges from 50 to 250 ml per dose of medicinal product to be administered.
    When Glucose 5% is used as a diluent for injectable preparations of other drugs, the dosage and the infusion rate will be principally dictated by the nature and the dose regimen of the prescribed drug.
    Paediatric population: The infusion rate and volume depends on the age, weight, clinical and metabolic conditions of the patient, concomitant therapy and should be determined by the consulting physician experienced in paediatric intravenous fluid therapy.
    Method of Administration: The solution is for administration by intravenous infusion (peripheral or central vein). When the solution is used for dilution and delivery of therapeutic additives for administration by intravenous infusion, the direction for use with additive therapeutic substances will dictate the appropriate volumes for each therapy.


    Indications

    The treatment of carbohydrate and fluid depletion. As a vehicle and diluent for compatible medicinal products for parenteral administration.


    Contra-Indications

    The solution is contraindicated in case of uncompensated diabetes, other known glucose intolerances (such as metabolic stress situations), hyperosmolar coma, hyperglycaemia, hyperlactatemia. Hypersensitivity to the active substance.

     


    Special Precautions

    See prescribing information for full details.


    Side Effects

    See prescribing information for full details.


    Drug interactions

    Both the glycaemic effects of Glucose 5% and its effects on water and electrolyte balance should be taken into account when using Glucose 5% in patients treated with other substances that affect glycaemic control, or fluid and/or electrolyte balance.
    Concomitant administration of catecholamines and steroids decreases the glucose up-take.
    No interaction studies have been performed.


    Pregnancy and Lactation

    Pregnancy: Glucose solution can be used during pregnancy. However, caution should be exercised when glucose solution is used intrapartum.
    Lactation: There are no adequate data of using Glucose solution during lactation. However, no effect on lactation is expected. Glucose 5% can be used during lactation.


    Overdose

    Prolonged administration or rapid infusion of large volumes of Glucose 5% may cause hyperosmolarity and hyponatraemia, dehydration, hyperglycaemia, hyperglycosuria, osmotic diuresis (due to the hyperglycaemia) and water intoxication and oedema. Severe hyperglycaemia and hyponatraemia, may be fatal.
    In case of suspected overdose, treatment with Glucose 5% must be stopped immediately. Management of overdose is symptomatic and supportive, with appropriate monitoring.


    Important notes

    Storage: 50 mL, 100 mL bags: Do not store above 30°C.
    250 mL, 500 mL, 1000 mL bags: This medicinal product does not require any special storage conditions.


    Manufacturer
    Baxter Healthcare Ltd., UK
    CLOSE