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  • Gardasil
    / MSD


    Active Ingredient
    Protein L1 20 μg HPV 6 L1 protein, 40 μg HPV 11 L1 protein, 40 μg HPV 16 L1 protein, 20 μg HPV 18 ml 1 protein.

    Status in Israel
    RX

    Presentation and Status in Health Basket

    Presentation Basket Yarpa Pharmasoft

    Pre-filled Syringe (solution for injection)

    1 X 0.5 ml

    partial basket chart 6610 7820

    Dosage

    The usually recommended vaccination schedule is:
    If you are from 9 to and including 13 years of age: GARDASIL can be administered according to a 2-dose schedule:
    – First injection: at chosen date
    – Second injection: 6 months after first injection
    If the second vaccine dose is administered earlier than 6 months after the first dose, a third dose should always be administered.
    Alternatively, GARDASIL can be administered according to a 3-dose schedule:
    – First injection: at chosen date
    – Second injection: 2 months after first injection
    – Third injection: 6 months after first injection
    The second dose should be administered at least one month after the first dose and the third dose should be administered at least 3 months after the second dose. All three doses should be given within a 1-year period. Please speak to your doctor for more information.
    If you are from 14 years of age: GARDASIL should be administered according to a 3-dose schedule:
    – First injection: at chosen date
    – Second injection: 2 months after first injection
    – Third injection: 6 months after first injection
    The second dose should be administered at least one month after the first dose and the third dose should be administered at least 3 months after the second dose. All three doses should be given within a 1-year period. Please speak to your doctor for more information.
    It is recommended that individuals who receive a first dose of GARDASIL complete the vaccination course with GARDASIL.
    The vaccine should not be mixed in the same syringe with any other vaccines and solutions.


    Indications

    For females aged 9 through 45 years, for the prevention of cervical, vulvar, and vaginal cancer, precancerous or dysplastic lesions, genital warts, and infection caused by Human Papillomavirus (HPV) types 6, 11, 16, and 18 (which are included in the vaccine). For males aged 9 through 15 years for the prevention of infection caused by Human Papillomavirus (HPV) Types 6, 11, 16, and 18 (which are included in the vaccine).Immunogenicity studies have been conducted to link efficacy in females aged 16 to 26 years to the younger populations.


    Contra-Indications

    Hypersensitivity to the active substances or to any of the excipients of the vaccine. Individuals who develop symptoms indicative of hypersensitivity after receiving a dose of the vaccine should not receive further doses.


    Special Precautions

    As for any vaccine, vaccination may not result in protection in all vaccine recipients. Not intended to be used for treatment of active genital warts; cervical cancer; CIN, VIN or VaIN.
    Pregnancy and lactation: Should be given during pregnancy only if clearly needed. Caution should be exercised when administered to a nursing woman.


    Side Effects

    Mild pain, swelling, erythema.


    Drug interactions

    May be administered simultaneously with other vaccines or immunoglobulins provided two different injection sites are used, as well as different syringes.


    Manufacturer
    Merck Sharp & Dohme Corp., USA

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