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  • Pyrimidine Analogues
    6 Drugs classified under this drug class


    All the Drug Class Drugs

    Alexan
    Novartis
    RX
    partial basket chart
    Alexan

    Pyrimidine Analogues. Cytarabine 20 mg/ml, 50 mg/ml.
    VIAL (ready for use): 1 x 100 mg (5 ml);
    500 mg (10 ml); 1,000 mg (20 ml), 2,000
    mg (40 ml). See lit.
    Neoplastic dis.
    C/I: Known hypersens. to drug, bone
    marrow suppress.

    Capecitabine Teva
    Abic
    RX
    partial basket chart
    Capecitabine Teva

    Pyrimidine Analogues. Capecitabine 150 mg, 500 mg.
    TABS: Capecitabine 150×60,
    500mg×120.
    Dosage must be ajust. individ. accord.
    to the pt. med. cond.
    Adjuv. colon cancer foll. surg. of stage III
    (Duke’s stage C) colon cancer. Metastatic breast cancer in comb. with docetaxel aft.
    fail of prior anthracycline-cont.
    chemotherapy, as monother. advanced or
    metastat. breast cancer aft. fail. standard
    ther. incl. a taxane, unless ther. with a
    taxane is clinic. contraindicat. Advanced
    or metastat. colorectal cancer. First line
    tmt. advanced gastric cancer in comb.
    with chemother.
    C/I: Hist. of severe, unexpec. react. to
    fluoropyrimidine ther.; Hypersens. to
    capecitabine or to fluorouracil; Pts. with
    known (DPD) defic.; Preg.; lact.; Pts. with
    sev. leukopenia, neutropenia, or
    thrombocytopenia; sev. hep. impair.; Pts.
    with severe renal impair. (CrCl ≤ 30 ml/
    min); Tmt. with sorivudine or its chemic.
    related analog. , (e.g. brivudine); If
    contraind. exist to any of the med.
    products in the comb. regimen, that
    med. product should not be used.

    Cytosar 1 g
    Pfizer
    RX
    partial basket chart
    Cytosar 1 g

    Pyrimidine Analogues. Cytarabine 1g/Vial.
    VIAL: 1. Convent. dose: In the induct. ther. of acute non-lymphocyt. leukemia, the
    usual cytarabine dose in comb. with
    other anti-cancer drugs is 100 mg/
    m2/d by cont. I.V. infus. (1st -7th d.) or
    100 mg/m2 I.V. every 12 hrs. (1st -7th
    d.). High dose: 2-3 g/m2 as an I.V. infus.
    over 1-3 hors given every 12 hours for
    2-6 d. with/ without addit. cancer
    chemother. agents.
    Induct. and mainten. remiss. in acute
    myelocytic leukemia of adults & child.
    Tmt. of other leukemias. See Lit.
    C/I: Pts. with pre exist. drug induced
    bone marrow suppres. unless the clin.
    feels that such manage. offers the most
    hopeful alternative for the pt.
    Manag. of non malignant dis., except for
    immunosuppress.Hypersens.

    Gemcitabin “Ebewe” 40 mg/ml
    Pharmalogic
    RX
    partial basket chart
    Gemcitabin “Ebewe” 40 mg/ml

    Pyrimidine Analogues. Gemcitabine (HCl) 4 mg/ml.
    VIAL (conc. for sol. for infus.): 1 x 200 mg
    x 40 mg/ml; 1 x 1,000 mg x 40 mg/ml.
    I.V. Adjust. accord. indicats, gen. cond.,
    hepat./ren. funct., concur. chemother.,
    bl. counts. See lit.
    Pall. tmt in local. advanced/ metastat.
    NSCLC, local. advanced/metastat.
    adenocarcinoma pancreas, 5-FU refract.
    pancreat. cancer, bladder cancer at invas.
    stage. In combinat. with paclitaxel for tmt
    pts. with unresect. local. recur./metastat.
    breast cancer who have relapsed follow.
    adjuv./neoadjuv. chemother. Prior
    chemother. should have included
    anthracycline unless C/I. In comb. with
    carboplatin for recur. epithelial ovarian
    carcinoma that has relapsed at least 6
    mths aft. platinum based ther.
    C/I: Hypersens., pregn., lact. See lit.

    Gemcitabine Medac
    Tzamal
    RX
    partial basket chart
    Gemcitabine Medac

    Pyrimidine Analogues. Gemcitabine (HCl) 200, 1000, 1500 mg.
    VIALS: 1. I.V. Adjust. accord. indicats,
    gen. cond., hepat./ren. funct., concur.
    chemother., bl. counts. See lit.
    Pall. tmt in local. advanced/ metastat.
    NSCLC, local. advanced/metastat.
    adenocarcinoma pancreas, 5-FU refract.
    pancreat. cancer, bladder cancer at invas.
    stage. In combinat. with paclitaxel for tmt
    pts. with unresect. local. recur./metastat.
    breast cancer who have relapsed follow.
    adjuv./neoadjuv. chemother. Prior
    chemother. should have included
    anthracycline unless C/I. In comb. with
    carboplatin for recur. epithelial ovarian
    carcinoma that has relapsed at least 6
    mths aft. platinum based ther.
    C/I: Hypersens., lact. See lit.

    Gemcitabine Teva Concentrate
    Abic
    RX
    partial basket chart
    Gemcitabine Teva Concentrate

    Pyrimidine Analogues. Gemcitabine (as HCl) 40 mg/ml.
    VIALS (concentrate for sol. for infus.) of 5,
    25, 50 ml x 1. Dosage must be individ. adjust. for each pt. accord. to the medical condit. Not to be used in children under 18
    years of age.
    Palliative tmt. of adult pts. with local.
    advance.,metast. non-small cell lung can.,
    local. advance., metast. adenocarcin. of
    the pancr., pts. with 5-FU refract. panc.can.
    Tmt. of pts. with bladder can. at the invas.
    stage.
    Breast can.: In comb. with paclitaxel, for
    the tmt. of pts. with unresect. local.recur.,
    metast. breast can. who have relapsed
    follow. adjuvant/neoadjuv. chemother.
    Prior chemother. should have include. an
    anthracycline unless clinic.contraind.
    Ovar. can.: In comb.with carboplatin; tmt.
    of pts. with recur. epith. ovar. carcin. who
    have relapsed at least 6 mts. after
    platinum-based ther.
    C/I: Hypersens. lact.

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