All the Drug Class Drugs
Other Cephalosporins & Penems. Ceftolozane 1 g, Tazobactam 0.5 g. VIAL (Pwdr. for concentrate for sol. for infus.): 10. The recomm. IV dose regimen for pts. with CrCl>50 mL/min.
Complicated intra-abdom. infec.*: 1 g ceftolozane/0.5 g tazobactam (To be used in comb. with metronidazole when anaerobic pathogens are suspected.) every 8 hrs., Infus. time 1 h, duration of the tmt. 4-14 days.
Complicated UTI's, acute pyelonephritis: 1 g ceftolozane/0.5 g tazobactam, every 8 hrs., infus. time 1h, 7 days.
Complic. intra-abdom. infec.
Acute pyelonephritis caused by pathogens resist. to other tmts. as confirmed by urine culture.
Complic. UTI.
Consid. should be given to official guidance on the appropriate use of antibact. agents.
C/I: Hypersens. Hypersens. to any cephalosporin antibact. agent.
Severe hypersens. (e.g., anaphylactic reaction, severe skin reaction) to any other type of beta-lactam antibact. agent (e.g., penicillins or carbapenems).
Other Cephalosporins & Penems. Ceftaroline Fosamil 600 mg. VIAL.: 10. The recommend. tmt. durat. for cSSTI is 5 to 14 days and the recommend. durat. of tmt. for CAP is 5 to 7 days.
Adult. with normal ren. func., (CrCL) > 50 mL/min: cSSTI, CAP-600 mg, infus. 60 min. every 12 hrs.
Ped. pts. with norm. ren. func., (CrCL) > 50 mL/min. (Calculat. using the Schwartz form. (in mL/min/1.73 m²) for paed. pts.).
cSSTI: Adolesc. aged 12 to<18 yrs. with bdy. wt.≥33 kg-600mg, infus. 60 min. every 12 hrs.
Adolesc. 12 yrs. to<18 yrs. bdy. wt.<33 kg and child.≥2 yrs. to<12 yrs Calculat. using the Schwartz form. (in mL/min/1.73 m²) for paed. pts.) -12 mg/kg to a max. of 400 mg, infus. 60 min. every 8 hrs.
CAP: Infant.≥2 mnths. to<2 yrs.- 8 mg/kg, infus. 60 min every 8 hrs.
Dosage in adults & adolesc. with impair. ren. func., (CrCL)≤ 50 mL/min: See lit.
Indicated in adult. & child. from age of 2 mnths. for the tmt. of the following infec.:
Complic. skin&soft tissue infec. (cSSTI).
Community-acquir. pneumon. (CAP) Consider. should be given to official guidance on the appropriate use of antibact. agents.
C/I: Hypersens. to the act. subst. or it’s excip. Hypersens. to the cephalosp. class of antib. Anaphyl. react. to any other type of beta-lactam antib. (e.g. penicillins or carbapenems.).
