Kallikrein Inhibitor Berotralstat

1 Drug classified under this drug class

Drugs used in Hereditary Angioedema, Kallikrein Inhibitor Berotralstat. Berotralstat 110 mg, 150 mg.
Caps. 110/150 mg X 28
150 mg orally once/d. Mod. or sev. hepatic imp. (Child-Pugh B or C): 110 mg /d. Pts. with chronic admin. of P-gp or BCRP inhibit. (e.g., cyclosporine): 110 mg /d
Prevent. of attacks of hereditary angioedema (HAE) in adlts. and ped. pts. 12 years and older. Limit. of use: safety and effectiv. for tmt. of ac. HAE attacks have not been establish., not be used for acute HAE attacks. Addit. doses or doses higher than 150 mg are not recomm. due to the potent. for QT prolong.
C/I: Hypersens.