All the Drug Class Drugs
Drugs used in Hereditary Angioedema, Kallikrein Inhibitor Berotralstat. Berotralstat 110 mg, 150 mg. Caps. 110/150 mg X 28
150 mg orally once/d. Mod. or sev. hepatic imp. (Child-Pugh B or C): 110 mg /d. Pts. with chronic admin. of P-gp or BCRP inhibit. (e.g., cyclosporine): 110 mg /d
Prevent. of attacks of hereditary angioedema (HAE) in adlts. and ped. pts. 12 years and older. Limit. of use: safety and effectiv. for tmt. of ac. HAE attacks have not been establish., not be used for acute HAE attacks. Addit. doses or doses higher than 150 mg are not recomm. due to the potent. for QT prolong.
C/I: Hypersens.
Drugs used in Hereditary Angioedema. Conestat Alfa 2100 U/25ml. VIAL: 1x 25ml. Adults up to 84 kg body
weight: One IV inj. of 50 U/kg bdy wt.
Adults of 84 kg bdy wt or greater: One
IV inj. of 4200 U (2 vials).
For tmt. of acute angioedema attacks in
adults with hereditary angioedema (HAE)
due to C1 esterase inhibitor deficiency.
C/I: Hypersens., known or susp. allergy
to rabbits.
