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  • Folic Acid Derivative
    2 Drugs classified under this drug class

    All the Drug Class Drugs

    Leucovorin 10 mg/ml
    Salomon, Levin & Elstein Ltd
    partial basket chart
    Leucovorin 10 mg/ml

    Folic Acid Derivative. Calcium Folinate 10 mg/ml.
    VIALS (sol. for inj.): 5 ml, 10 ml, 20 ml, 30
    ml, 50 ml x 10 mg/ml.
    Dosage must be ajust. individ. for each
    pt. accord. to pt. med. cond.
    To diminish the toxic. and counteract the
    action of folic acid antagonists in
    cytotoxic ther. As Leucovorin-Fluorouracil
    chemother. comb. for cancer tmt.
    C/I: Hypersens.

    Leucovorin Teva Tablets
    full basket chart
    Leucovorin Teva Tablets

    Folic Acid Derivative. Calcium Folinate 15 mg.
    TABS.: 10,12×15 mg. For oral admin.
    Calcium Folinate Rescue: Adults & Child.: In general up to 120mg in divided doses over 12 - 24 hrs. by IM  inject., bolus IV inj., or IV infus. in 0.9% w/v NaCl sol. follow. by 12 - 15mg IM or 15 mg oral., every 6 hrs. for the next 48 hrs.
    Calcium Folinate should not be given simultan. with methotrexate as it may reduce or suppress its anti-neoplast. activity. It is recomm. that admin. should commence within the first 24 hrs. follow. methotrexate. In overdose situations or when the half-life of methotrexate is incr.(e.g. renal funct. impair.or pleural or periton.  effusions) it is important that Calcium Folinate be given until the blood conc. of methotrexate declines to non-toxic conc. In these cases, doses of Calcium Folinate equal to or greater than those of methotrexate should be given.
    Folinate defic.: Adults: 15mg (one tab.)×1/d.
    Child. up to 12 yrs.: 0.25mg/kg.day.
    See Lit.
    Counteracts the action of folic acid antagon. Improves blood picture in megaloblastic anemias due to folate defic.
    C/I: Hypersens.