Enzyme Replacement Therapy

5 Drugs classified under this drug class

Enzyme Replacement Therapy. Laronidase 500 U / 5 ml.
VIAL: 1. See lit.
Long-term enzyme replace. ther. in
confirm. mucopolysaccharidos. I
(MPS I, alfa-I-iduronidase defic.) for nonneurolog. manifests. of the dis.

Enzyme Replacement Therapy. Imiglucerase 400 U/Vial.
VIAL (lyophilized pwdr. for infus.): 1.
See lit.
Long term enzyme replace. ther. in
confirmed diagn. type 1 Gaucher dis.

Enzyme Replacement Therapy. Agalsidase Beta 5 mg/ml, 35 mg/7ml.
PWDR. FOR INFUS: 1 x 5 mg/ml,
35 mg/ml. See lit.
Long-term enzyme replace. ther. in
confirmed diagnos. Fabry dis. (alfagalactosidase A defic.).

Enzyme Replacement Therapy. Velmanase alfa 10 mg/vial.
Pwder for sol. for infus.: 10 mg/vial.
Dose 1 mg/kg of BW admin. once / week by IV infus. at a contr. speed .
 Enzyme replac. ther. for the trt. of non-neurol. manifest. in pts. with mild to mod. alpha-mannosidosis
C/I:Hypersens.

Enzyme Replacement Therapy. Alglucoside Alfa 50 mg.
VIAL (pwdr. for conc. infus. sol.): 1.
20 mg/kg bdy wt I.V. infus. every 2 wks.
Initial rate: 1 mg/ kg/hr. Grad. incr. by 2
mg/kg/ hr. every 30 mins. if no signs
IARs, incr. until max. rate: 7 mg /kg/hr.
Tmt. by physician experienced in manage.
Pompe dis. or other inherited
metabol./neuromusc. dis.
Long-term enzyme replace. ther. (ERT) in
comfirmed Pompe dis.(acid alphaglucosidase
defic.).
The benefits in pts with late-onset Pompe
dis. have not been establ.
C/I: Life-threat. hypersens., when rechall.
was unsuccessful.