All the Drug Class Drugs
Colony Stimulating Factor. Lipegfilgrastim 6 mg / 0.6 ml. PREFILLED SYRINGE (sol. for inj.): 1 × 0.6
ml. One 6 mg dose of (a single pref.
syr.) for each chemoth. cycle, given approx. 24 hrs. after cytotoxic
Reduct. in the durat. of neutropenia and
the incidence of febrile neutropenia in
adult pts. treated with cytotoxic
chemother. for malignan. (with the
except. of chron. myeloid leukaemia and
Colony Stimulating Factor. Pegfilgrastim 6 mg / 0.6 ml. PREFILL SYRINGE (ready-to-use) 1 x 6
mg/0.06 ml. One 6 mg dose for ea.
chemother. cycle S.C. inject. approx.
24 hrs follow. cytotox. chemother.
Reduct. durat. neutropen., incidence of
febrile neutropen. in pts. treated with cytotox. chemother. for malignancy (with
the except. of chron. myeloid leukem. and
Colony Stimulating Factor. Filgrastim 30 MU/ml (0.3 mg/ml), 30 MU/0.5 ml (0.6 mg/ml), 48 MU/0.5 ml (0.96 mg/ml). VIALS (sol. for inj.): 5×30MU (0.3 mg/
PREF. SYR. (sol. for inj.): 5×30MU (0.6 mg/
ml), 1, 5×48MU (0.96 mg/ml). Dosage ajust. individ. accord. pt. med. condition.
Reduct. in the duration of neutropenia and
the incidence of febrile neutropenia in pts.
treated with established cytotoxic
chemother. for malign. (with the exception
of chronic myeloid leukaemia and
myelodysplastic syndr.) and for the reduct.
in the duration of neutropenia in pts.
undergoing myeloablative ther. followed
by bone marrow transplant., considered
to be at incr. risk of prolon. severe
neutropenia. The safety and efficacy of
Filgrastim are similar in adults and child.
receiving cytotoxic chemother. Indic. for
the mobilisation of peripheral blood
progenitor cells (PBPCs). In pts., children/
adults, with severe congen., cyclic or
idiopathic neutropenia with an ANC of
≤0.5 ×10^9/l, and a history of severe or
recurrent infec., long-term admin. of this
drug is indicated to increase neutrophil
counts and to reduce the incidence and
duration of infect.-related events.
C/I: Hypersens. Filgrastim should not be
diluted with saline sol. Diluted filgrastim
may be adsorbed to glass and plast.
Colony Stimulating Factor. Filgrastim 0.6 mg/ml. PREFILLED SYRINGE: 1, 5, 10 x 30
MIU/0.5 ml, 48 MIU/0.8 ml.
0.5 MIU (5 μg)-1.2 MIU (12μg)/kg dly.
Reduct. durat. neutropen., febrile
neutropen. in pts. treated with establish.
cytotoxic chemother. for malign. (except
chron. myeloid leukem., myelodysplast.
syndr.); reduct. durat. neutropen. in
myeloablat. ther. foll. by bone marrow
transplant. at incr. risk of prolong. Severe
neutropen. For mobilisat. periph. Blood
progenitor cells in normal donors. Long
term admin. to incr. neutrophil counts
and reduce incidence and durat. of
events in pts. with severe congen., cyclic,
or idiopath. neutropen. with absolute
neutrophil count (ANC) of 0.5 x 109/l and
history of severe or recurr. infects. Tmt.
persist. neutropen, (ANC < 1.0 x 109/l) in
advanced HIV infect., to reduce risk of
infect. when other options inapprop.
C/I: Known hypersens.