All the Drug Class Drugs
Antigrowth Hormone. Octreotide 0.05, 0.1, 0.5 mg/ml. AMPS (sol. for inject./infus.): 5 x 0.05, 0.1,
0.5 mg/ml.
Dosage must be ajust. individ. See lit.
Prevent. complicats. follow. pancreat.
surg., symptomat. control and reduct. GH
and IGF-1 plasma levels in pts. with
ecromegaly who are inadequate.
controlled by surg., radiother. or dopamine agonist. Acromegalic unfit or unwilling to undergo surg., or in the interim period until
radiother. becomes fully affect. Relief of
sympts. associated with gastroenteropancreat.
endocrin tumors: carcinoid tumors with features of the carcinoid syndr.; VIPomas; glucagonomas; gastrinomas / Zollinger- Ellison syndr. usually in conjunct. with select
H2-antagonist ther; insulinomas, for preop.
control of hypoglycem., for maint. ther.; GRFomas. Not antitumor ther., not
curative in these pts. Emergency manage.
Bleed gastro-esoph. varices second. to
cirrhos. In comb. specific ther. such as
sclerother.
C/I: Hypersens.
Antigrowth Hormone. Pasireotide 0.3. 0.6, 0.9 mg/ml. AMPS: 30, 60 x 0.3 mg/ ml, 0.6 mg/ ml,
0.9 mg/ ml.
S.C inj., prefer. in top of thighs and
abdomen. Adults: init.: 0.6 mg x 2 dly.
for 2 mths. Then adjust accord. to pts. response and advers, react. Child.: no
data. Hepatic impair. see lit.
Tmt. of adult pts with Cushing’s disease
for whom surgery is not an option or for
whom surgery has failed.
C/I: Hypersens., Severe hepatic impair.
(Child Pugh C).
