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  • Alkylating Agent (platinum analog)
    5 Drugs classified under this drug class


    All the Drug Class Drugs

    Abiplatin 1 mg/ml
    Salomon, Levin & Elstein Ltd
    RX
    partial basket chart
    Abiplatin 1 mg/ml

    Alkylating Agent (platinum analog). Cisplatin 1 mg/ml.
    VIALS: 1 x 100 ml, 50 ml. See lit.
    Palliative in add. to other modalities
    in
    tmt. metastat. testic. and ovar. cancer,
    advanced bladder cancer.

    Carboplatin
    Salomon, Levin & Elstein Ltd
    RX
    partial basket chart
    Carboplatin

    Alkylating Agent (platinum analog). Carboplatin 10 mg/ml.
    VIALS (Conc. for sol. for infus.): 1 x 5 ml,
    15 ml, 45 ml, 60 ml. Dosage must be
    ajust. individ. accord. to pt. med. cond.
    Advanced ovar. carcinoma in initial tmt.
    and secondary tmt. Metastatic small cell
    carcinoma of the lung.
    C/I: Severe renal impair. (CrCL< 20 ml/
    min), severe myelosuppress., Hypersens.
    to platinum compounds or mannitol,
    pts with bleeding tumours, lact.

    Eloxatin
    Sanofi
    RX
    partial basket chart
    Eloxatin

    Alkylating Agent (platinum analog). Oxaliplatin 5 mg/ml.
    SOLN (conc. for infus.): 10 ml, 20 ml, 40 ml. Adults only. Adjuv. setting: 85 mg/m2 I.V. every 2 wks for 12 cycles (6 mths). Metastat. colorect. cancer: 85 mg/m2 I.V. every 2 wks.
    In comb. with fluorouracil and folic acid for adjuv. tmt. stage III (Duke’s C) colon cancer aft. complete resect. prim. tumor, metastat. colorect. cancer.

    Oxaliplatin Medac
    Tzamal
    RX
    partial basket chart
    Oxaliplatin Medac

    Alkylating Agent (platinum analog). Oxaliplatin 50, 100, 150 mg.
    VIAL: 1 x 50 mg, 100 mg, 150 mg
    (reconstitut. soln: 5 mg/ml oxaliplatin).
    Adults only. Adjuv. setting: 85 mg/m²
    I.V. Repeat every 2 wks. for 12 cycles (6
    mths). Metastat. colorect. cancer: 85
    mg/m2 I.V. Repeat every 2 wks. Adjust
    dose accord. tolerability. Always
    admin. bef. fluoropyramidines. See lit.
    In comb. with 5-fluorouracil (5-FU) and
    folinic acid for adjuv. tmt. stage III (Duke’s
    C) colon cancer aft. complete resect.
    primary tumor, tmt. metastat. colorect.
    cancer.
    C/I: Hypersens., lact., myelosuppress.
    prior to 1st course, peripheral sens.
    neuropath prior to 1st course, severe
    impair. ren. funct.

    Oxaliplatin Teva
    Salomon, Levin & Elstein Ltd
    RX
    partial basket chart
    Oxaliplatin Teva

    Alkylating Agent (platinum analog). Oxaliplatin 5 mg/ml.
    VIALS (conc. for sol. for infus.): 1 x 10 ml,
    20 ml, 40 ml. For I.V. infus., adults only. See lit.
    Adjuv. setting: Metastat. colorect.
    cancer: 85 mg/m2 repeat. every 2 wks
    for 12 cycles (6 mths). Admin. as a 2-6
    hr I.V. infus. in 5% glucose sol. (see lit.).
    Mainly used in comb. with cont. infus.
    5-FU based regimens. Ren. impair:
    Mild-mod: Init. normal recommend.
    dose. Severe: No data. Hepat. impair:
    No specific dose adjusts. test
    performed during clin. develop.
    Elderly: No specific dose adjusts.
    Should always be admin. bef.
    fluoropyramidines.
    In comb. with 5-fluorouracil (5-FU) and
    folinic acid (FA) for adjuv. tmt. stage III
    (Duke’s C) colon cancer aft. complete
    resect. prim. tumor; tmt. metastat.
    colorect. cancer.
    C/I: Hypersens., lact., periph. sens.
    neuropathy with funct. impair. prior to
    1st course; myelosuppress. prior to start.
    1st course, severe impair. ren. funct.
    (creatinine clear. < 30 ml/min).

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