ALK

1 Drug classified under this drug class

ALK, Tyrosine Kinase Inhibitor. Lorlatinib 25 mg, 100 mg.
F.C. TABS.: 90, 120×25mg, 30×100mg. 100 mg×1/day orally, with/without food, at the same time each day, until dis. progress. or unacceptab. toxic.
Swallow tablets whole. If a dose is missed, then the missed dose should be taken, unless the next dose is due within 4 hrs. If vomit. occurs after lorlatinib cont. with the next scheduled dose. 2 doses should not be taken at the same time to make up for a missed dose. See lit.
Tmt. of adult pts. with metast. NSCLC whose tumors are anaplast. lymphom. kinase (ALK)-positive.
C/I: Pts. taking strong CYP3A induc., due to the potential for serious hepatotox. Hypers.