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  • Rivaroxaban
    4 Drugs classified under this active ingredient


    All the Active Ingredient Drugs

    Xarelto 10 mg
    Bayer
    RX
    partial basket chart
    Xarelto 10 mg

    Factor Xa Inhibitor. Rivaroxaban 10 mg.
    F.C. TABS: 30. Recommend. dose: 10 mg
    orally 1 x dly, initial dose: 6-10 hrs aft. surg. Tmt. durat. acc. to type of surg.
    See lit.
    Prevent. VTE in adult pts. undergoing
    elective hip/knee replace. surg.
    C/I: Hypersens. to active substance or
    any of the excips., clin. signif. active
    bleed., hepat. dis. assoc. with
    coagulopathy and clin. relevant bleed.
    risk, pregnancy, lact.

    Xarelto 15 mg
    Bayer
    RX
    partial basket chart
    Xarelto 15 mg

    Factor Xa Inhibitor. Rivaroxaban 15 mg.
    F.C. TABS: 7, 14, 28, 42, 98, 100 x 15 mg. Dosage must be ajust individ. accord. to pt. med. cond.
    Prevent. of stroke & system. embolism in
    adult pts. with non-valvular AF with one
    or more risk factor., such as CHF,
    hypertens., age≥75 yrs., diab. mell., prior
    stroke or TIA. Tmt. of DVT and PE, and
    prevent. of recurrent DVT and PE in
    adults. See.lit.
    C/I: Hypersens. Active clinical. signific.
    bleed. Lesion / cond., if considered to be
    a signific. risk for major bleed. (e.g:
    current/ recent GI ulcer., presence of
    malign. neoplasms at high risk of bleed. ,
    recent brain/ spinal inj., recent brain,
    spinal or ophthal. surg., recent intracran.
    haemorrhage, known/ suspect.
    esophagi. varices, arterioven. malfor. ,
    vasc. aneurysms/ major intraspinal or
    intracereb. vasc. abnormalit. Concom.
    tmt. with any other anticoagul. e.g.
    unfraction. heparin, low molec. weight
    heparins (enoxaparin, dalteparin, etc.),
    heparin derivate.(fondaparinux, etc.),
    oral anticoag. (warfarin, dabigatran
    etexilate, apixaban, etc.) except under
    specific circumst. of switch. anticoag.
    ther. or when unfraction. heparin is
    given at doses necessary to maint. an
    open cent. venous/arter. catheter.
    Hep. dis. assoc. with coagulopathy and
    clinical. relevant bleed. risk include.
    cirrhotic pts. with Child Pugh B and C.
    Preg., lact.

    Xarelto 2.5 mg
    Bayer
    RX
    not in the basket chart
    Xarelto 2.5 mg

    Direct Factor Xa Inhibitor. Rivaroxaban 2.5 mg.
    TABS.: 14, 56, 60, 168
    The recomm. dose is 2.5 mg×2/d. Pts. should also take a daily dose of 75 - 100 mg ASA or a dly. dose of 75 - 100 mg ASA in addit. to either a dly. dose of 75 mg clopidogrel. Tmt. should be regularly evaluated in the individ. pt. weighing the risk for ischaem. events against the bleed. risks. Extens. of tmt. beyond 12 mnths. should be done on an individ.pt. Tmt. should be started as soon as possible after stabilisat. of the ACS event (includ. revascularisat. procedures); at the earliest 24 hrs. after admis.to hospital and at the time when parenteral anticoagul. ther. would normally be discont. If a dose is missed the pt. should cont. with the regular dose as recommend. at the next scheduled time. The dose
    should not be doubled to make up for a missed dose.
    Co-admin. with acetylsalicylic acid (ASA) alone or with ASA plus clopidogrel , is indic. for the prevent. atherothrombotic events in adult pts. after an acute coronary syndr. (ACS) with elevated card. biomarkers.
    C/I: Hypersens. Active clinical. signific. bleed. Lesion or condit. , if consid. to be a signific. risk for major bleed. This may include current or recent GI ulcerat., presence of malignant neoplasm. at high
    risk of bleed., recent brain or spinal injury, recent brain, spinal or ophthalmic surg., recent intracran. haemorrhage, known or suspected oesophageal varices, arterioven. malformat., vascular aneurysms or major intraspin. or intracereb. vascular abnormal. Concom. tmt. with any other anticoagulant.e.g. unfractionat. heparin, low MW hepar. (enoxaparin, dalteparin, etc.), heparin derivatives (fondaparinux,
    etc.), oral anticoag. (warfarin, dabigatran etexilate, apixaban, etc.) except under specific circumstan. of switching anticoag. ther. or when UFH is given at doses necessary to maintain an open central venous or arterial catheter. Concom. tmt. of ACS with antiplatelet ther. in pts. with a prior stroke or a TIA. Hep. dis. assoc. with coagulopathy and clinical. relevant bleed.risk include. cirrhotic pts. with Child Pugh B and C.
    Pregnancy and breast feeding

    Xarelto 20 mg
    Bayer
    RX
    partial basket chart
    Xarelto 20 mg

    Factor Xa Inhibitor. Rivaroxaban 20 mg.
    F.C. TABS: 7, 14, 28, 98, 100 x 20 mg mg. Dosage must be ajust individ. accord. to pt. med. cond.
    Prevent. of stroke & system. embolism in
    adult pts. with non-valvular AF with one
    or more risk factor., such as CHF,
    hypertens., age≥75 yrs., diab. mell., prior
    stroke or TIA. Tmt. of DVT and PE, and
    prevent. of recurrent DVT and PE in
    adults. See.lit.
    C/I: Hypersens. Active clinical. signific.
    bleed. Lesion / cond., if considered to be
    a signific. risk for major bleed. (e.g:
    current/ recent GI ulcer., presence of
    malign. neoplasms at high risk of bleed. ,
    recent brain/ spinal inj., recent brain,
    spinal or ophthal. surg., recent intracran.
    haemorrhage, known/ suspect.
    esophagi. varices, arterioven. malfor. ,
    vasc. aneurysms/ major intraspinal or
    intracereb. vasc. abnormalit. Concom.
    tmt. with any other anticoagul. e.g.
    unfraction. heparin, low molec. weight
    heparins (enoxaparin, dalteparin, etc.),
    heparin derivate.(fondaparinux, etc.),
    oral anticoag. (warfarin, dabigatran
    etexilate, apixaban, etc.) except under
    specific circumst. of switch. anticoag.
    ther. or when unfraction. heparin is
    given at doses necessary to maint. an
    open cent. venous/arter. catheter.
    Hep. dis. assoc. with coagulopathy and
    clinical. relevant bleed. risk include.
    cirrhotic pts. with Child Pugh B and C.
    Preg., lact.

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