Pramipexole Dihydrochloride Monohydrate

3 Drugs classified under this active ingredient

Domapine Agonist. Pramipexole Dihydrochloride Monohydrate 0.25, 1 mg.
TABS: 30, 50, 90, 100 x 0.25 mg, 1 mg.
With/out food in 3 equal divid. doses.
Not recommend. below 18 yrs.
Parkinson’s dis: 0.375 mg dly, incr.
every 5-7 days. Max: 4.5 mg dly.
Discont: Taper at rate of 0.75 mg dly
until dly dose of 0.75 mg, then reduce
by 0.375 mg dly. Restless legs syndr:
0.125 mg 1 x dly, 2-3 hrs. bef. bedt. May
incr. every 4-7 days to max. 0.75 mg
dly. Ren. impair: See lit. Hepat. impair:
No dos. adjust. See lit.
Tmt. signs/sympts. idiopath. Parkinson’s
dis. May be used as monother./comb.
with levodopa; sympt. tmt. mod-severe
idiopath. Restless legs syndrome (0.25 mg).
C/I: Hypersens., lact. comb. with
antipsychot. drugs.

Domapine Agonist. Pramipexole Dihydrochloride Monohydrate 0.25 mg, 1 mg.
TABS: 100 x 0.25 mg, 1 mg.
Parkinson’s disease: Init.: 0.125 mg x
3/d (ie 1/2 0.25 mg tab. t.i.d.); 2nd
week:
0.25 mg x 3/d; 3rd week.: 0.5 mg x 3/ d.
Titr. dose to achieve max. ther. effect. If
further dose incr. reqd. (partic. in
advanced Parkinson’s), incr. dly. Dose
by 0.75 mg salt at wkly..intervals up to
max. 4.5 mg salt dly. Dly. maint. dose:
Usually 0.375 mg-4.5 mg salt. Reduce
dos. levodopa. See lit. Restless legs
syndr: Init.: 0.125 mg salt x 1/d , 2-3 hrs.
bef. bedt. May incr. every 4-7 days to
max. 0.75 mg salt dly. Evaluate aft. 3
mths. tmt. See lit.
0.25 mg and 1 mg: tmt. of signs and
sympt. of idiopathic Parkinson’s dis., as
monother. or in comb. with levodopa.
0.25 mg is also indic. for sympt. tmt. of
moder.- sev. idiopath.Restless Legs Syndr.
C/I: Hypersen.

Domapine Agonist. Pramipexole Dihydrochloride Monohydrate 0.375. 0.75, 1.5, 4.5 mg.
E.R TABS: 10, 30 X 0.375 mg, 0.75 mg,
1.5 mg, 4.5 mg. once dly. Incr. grad.
Every 5-7 days. Init.:
0.375 mg tab. once dly, incr. - 0.75 mg
tab. 1 x dly to 1.5 mg 1 x dly. May incr. dose by 0.75 mg wkly. up to 4.5 mg dly.
Reduce dose levodopa in reqd. see lit.
Tmt. of signs and sympt. of idiopathic
Parkinson’s dis., as monother. or in comb.
with levodopa.
C/I: Hypersens.