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  • Palonosetron
    3 Drugs classified under this active ingredient

    All the Active Ingredient Drugs

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    Multiple ingredients

    5-HT3 Antagonist, Selective Antagonist of NK1 Receptors. Netupitant 300 mg, Palonosetron (hydrochloride) 0.5 mg.
    CAP.: 1. One 300 mg / 0.5 mg cap. should be administered approx. one h.  prior to the start of each chemother. cycle. The recommend. oral dexamethasone dose should be reduced by approx. 50 % when co-admin. with this formul.
    Preven.of acute & delayed nausea and vomit. assoc.  with init. and repeat courses of cancer chemoth., includ., but not limited to, highly emetogenic chemother.
    C/I: Hypersens., preg.

    Teva Israel LTD, Israel
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    Serotonin 2C Receptor Agonist. Palonosetron 0.05 mg/mi.
    Vial, Sol for IV inf., 1X 5ml
    250 microg admin. as a sgle IV bolus approx. 30 min. before  start of chemother. to be inject. over 30 seconds. The efficacy of this drug in the prevent. of nausea and vomit. induced by highly emetogenic chemother. may be enhanced by the addit. of a corticoster. admin. prior to chemother. Child. and adolesc. (aged 1 month to 17 years): 20 microg/kg (max. total dose should not exceed 1500 microg) palonosetron admin. as a sgle 15 min. IV infus. beginning approx. 30 min. before start of chemother.
    In adlts and in paed. ptts. 1 month of age and older for the prevent. of ac. nausea and vomit. assoc. with highly emetogenic cancer chemotherapy, and prevent. of nausea and vomit. assoc. with moder. emetogenic cancer chemotherapy.

    Paloxi Injection
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    Paloxi Injection

    5-HT3 Antagonist. Palonosetron (as HCl) 0.25 mg/vial.
    VIALS (sol. for inject.): 1 x 5 ml. 0.25 mg
    I.V. as single dose over 30 secs. approx.
    30 mins. bef. start chemo. Repeat.
    dose within 7-day interval not
    recommend. Not to be mixed with
    other drugs. Flush infus. line with
    normal saline bef. and aft. admin.
    Elderly/ren./hep. impair: No dose
    Prevent chemo.-induced naus. and
    vomit. (CINV).
    C/I: Hypersens.